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首页> 外文期刊>Journal of psychiatric research >Clinical, psychological and environmental predictors of prospective suicide events in patients with Bipolar Disorder
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Clinical, psychological and environmental predictors of prospective suicide events in patients with Bipolar Disorder

机译：双相情感障碍患者前瞻性自杀事件的临床，心理和环境预测因素

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Patients with Bipolar Disorder (BD) have high rates of suicide compared to the general population. The present study investigates the predictive power of baseline clinical, psychological and environmental characteristics as risk factors of prospective suicide events (attempts and completions). Data was collected from the Systematic Treatment Enhancement Program for Bipolar Disorder (STEP-BD) study. 3083 bipolar patients were included in this report, among these 140 (4.6%) had a suicide event (8 died by suicide and 132 attempted suicide). Evaluation and assessment forms were used to collect clinical, psychological and socio-demographic information. Chi-square and independent t-tests were used to evaluate baseline characteristics. Potential prospective predictors were selected on the basis of prior literature and using a screening analysis of all risk factors that were associated with a history of suicide attempt at baseline and were tested using a Cox regression analysis. The strongest predictor of a suicide event was a history of suicide attempt (hazard ratio=2.60, p-value<0.001) in line with prior literature. Additional predictors were: younger age, a high total score on the personality disorder questionnaire and a high percentage of days spent depressed in the year prior to study entry. In conclusion, the present findings may help clinicians to identify patients at high risk for suicidal behavior upon presentation for treatment.
机译：与一般人群相比，患有双相情感障碍（BD）的患者自杀率较高。本研究调查基线临床，心理和环境特征作为预期自杀事件（尝试和完成）的危险因素的预测能力。从双相情感障碍系统治疗增强计划（STEP-BD）研究中收集数据。该报告包括3083名双相情感障碍患者，其中140名（4.6％）有自杀事件（8名自杀死亡和132名自杀未遂）。评估和评估表用于收集临床，心理和社会人口统计学信息。卡方检验和独立t检验用于评估基线特征。在现有文献的基础上选择潜在的预期预测因素，并对所有与基线自杀尝试史相关的危险因素进行筛选分析，并使用Cox回归分析进行测试。自杀事件的最强预测因子是自杀尝试的历史（危险比= 2.60，p值<0.001），与现有文献一致。其他预测因素是：年龄较小，人格障碍问卷调查的总分较高，入学前一年的抑郁症天数较高。总之，本研究结果可帮助临床医生在就诊时确定自杀行为的高风险患者。

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