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首页> 外文期刊>Journal of palliative medicine >Predictive factors for agitation severity of hyperactive delirium in terminally ill cancer patients in a general hospital using ordered logistic regression analysis
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Predictive factors for agitation severity of hyperactive delirium in terminally ill cancer patients in a general hospital using ordered logistic regression analysis

机译：运用有序逻辑回归分析预测综合医院晚期癌症患者多动性ir妄躁动严重程度的预测因素

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Background: Despite the fact that many cancer patients worldwide die in general hospitals, there are few reports of the analysis of delirium in terminally ill cancer patients in this setting. Purpose: This study aimed to identify predictive factors for agitation severity of hyperactive delirium in terminally ill cancer patients in a general hospital. Methods: Participants were 182 consecutively admitted terminally ill cancer patients who died in a Japanese general hospital between April 2009 and March 2011. Variables present one week before death were extracted from the clinical records for regression analysis of factors potentially related to agitation severity of delirium. The prevalence and agitation severity of delirium were evaluated retrospectively. Multivariate ordered logistic regression analysis was performed to identify predictive factors. Results: Male sex [odds ratio (OR)=2.125, 95% confidence interval (CI)=1.111-4.067; P=0.0227]; total bilirubin (T-bil) [OR=1.557, CI=1.082-2.239; P=0.017]; antibiotics [OR=0.450, CI=0.219-0.925; P=0.0298]; nonsteroidal antiinflammatory drugs (NSAIDs) [OR=2.608, CI=1.374-4.950; P=0.0034]; and hematological malignancy [OR=3.903, CI=1.363-11.179; P=0.0112] were found to be statistically significant predictors for agitation severity of hyperactive delirium. Conclusions: Our study indicates that male sex, T-bil, antibiotic therapy, NSAID therapy, and hematological malignancy are significant predictors for agitation severity of hyperactive delirium in terminally ill cancer patients in a general hospital setting.
机译：背景：尽管世界各地有许多癌症患者死于综合医院，但在这种情况下很少有关于对绝症癌症患者进行del妄分析的报道。目的：本研究旨在确定综合医院绝症癌症患者多动性del妄躁动严重程度的预测因素。方法：参与者是2009年4月至2011年3月在日本综合医院死亡的182例连续入院的绝症患者。从临床记录中提取死亡前一周的变量，用于对与regression妄躁动严重程度可能相关的因素进行回归分析。回顾性评估ir妄的患病率和躁动严重程度。进行多元有序逻辑回归分析以识别预测因素。结果：男性[比值比（OR）= 2.125，95％置信区间（CI）= 1.111-4.067; P ＝ 0.0227];总胆红素（T-bil）[OR = 1.557，CI = 1.082-2.239; P ＝ 0.017];抗生素[OR = 0.450，CI = 0.219-0.925; P = 0.0298];非甾体类抗炎药（NSAIDs）[OR = 2.608，CI = 1.374-4.950; P = 0.0034];和血液系统恶性肿瘤[OR = 3.903，CI = 1.363-11.179; P = 0.0112]被发现是多动ir妄躁动严重程度的统计学显着预测因子。结论：我们的研究表明，在一般医院中，男性，T-bil，抗生素治疗，NSAID治疗和血液系统恶性肿瘤是绝症晚期患者多动性del妄躁动严重程度的重要预测指标。

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