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Associations between sleep habits and mental health status and suicidality in a longitudinal survey of monozygotic twin adolescents

机译:在单卵双生青少年的纵向调查中睡眠习惯与心理健康状况和自杀倾向之间的关联

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Several epidemiological studies have indicated that there is a relationship between sleep habits, such as sleep duration, bedtime and bedtime regularity, and mental health status, including depression and anxiety in adolescents. However, it is still to be clarified whether the relationship is direct cause-and-effect or mediated by the influence of genetic and other traits, i.e. quasi-correlation. To examine this issue, we conducted a twin study using a total of 314 data for monozygotic twins from a longitudinal survey of sleep habits and mental health status conducted in a unified junior and senior high school (grades 7-12), located in Tokyo, Japan. Three-level hierarchical linear model analysis showed that both bedtime and sleep duration had significant associations with the Japanese version of the 12-item General Health Questionnaire (GHQ-12) score, suicidal thoughts and the experience of self-harm behaviours when genetic factors and shared environmental factors, which were completely shared between co-twins, were controlled for. These associations were statistically significant even after controlling for bedtime regularity, which was also associated significantly with the GHQ-12 score. These suggest that the associations between sleep habits and mental health status were still statistically significant after controlling for the influence of genetic and shared environmental factors of twins, and that there may be a direct cause-and-effect in the relationship in adolescents. Thus, late bedtime and short sleep duration could predict subsequent development of depression and anxiety, including suicidal or self-injury risk. This suggests that poor mental health status in adolescents might be improved by health education and intervention concerning sleep and lifestyle habits.
机译:几项流行病学研究表明,睡眠习惯(如睡眠时间,就寝时间和就寝时间的规律性)与心理健康状况(包括青少年的抑郁症和焦虑症)之间存在关联。但是,该关系是直接的因果关系还是由遗传和其他性状的影响(即准相关性)介导,尚待阐明。为了研究这个问题,我们对一对单卵双胞胎进行了总共314项数据的双胞胎研究,这些数据来自在东京都初中和高中(7-12年级)统一进行的睡眠习惯和心理健康状况的纵向调查。日本。三级分层线性模型分析表明,就寝时间和睡眠时间与日语版的12个项目的《一般健康状况调查表》(GHQ-12)得分,自杀意向以及遗传因素和自残行为的经历之间存在显着关联。控制共享环境因素,这些因素在双胞胎之间完全共享。即使控制了就寝时间的规律性,这些关联也具有统计学意义,这也与GHQ-12得分显着相关。这些表明,在控制了双胞胎的遗传和共享环境因素的影响之后,睡眠习惯与心理健康状况之间的关联仍然具有统计学意义,并且青少年之间的关系可能存在直接的因果关系。因此,就寝时间晚和睡眠时间短可以预测抑郁症和焦虑症的后续发展,包括自杀或自残的风险。这表明可以通过健康教育和有关睡眠和生活方式习惯的干预措施来改善青少年不良的心理健康状况。

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