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首页> 外文期刊>Clinical EEG and neuroscience: official journal of the EEG and Clinical Neuroscience Society (ENCS) >A combined rTMS and ERP investigation of dorsolateral prefrontal cortex involvement in response inhibition.
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A combined rTMS and ERP investigation of dorsolateral prefrontal cortex involvement in response inhibition.

机译：rTMS和ERP的联合研究涉及对反应抑制的背外侧前额叶皮层的参与。

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摘要

The stop signal task is used to investigate inhibition of an initiated response. Converging evidence suggests that right inferior prefrontal cortex is involved in this behavior, although other regions in the prefrontal cortex have also been implicated. One technique used to determine the contribution of specific cortical regions to behavior is repetitive transcranial magnetic stimulation (rTMS). In the present study, fourteen subjects performed the stop signal task before and after receiving a train of rTMS to the left and right dorsolateral prefrontal cortex (DLPFC). The effects of rTMS were determined using event-related potential (ERP) measures that have been associated with response inhibition in previous studies. Stimulation of left and right DLPFC did not affect ERP measures of response inhibition. This negative finding is interpreted with caution, but is consistent with a recent study which found that stimulation of the same region had no effect on a behavioral measure of response inhibition.
机译：停止信号任务用于调查对启动响应的抑制。越来越多的证据表明，右前额叶下皮层参与了这种行为，尽管前额叶皮层中的其他区域也有牵连。用于确定特定皮质区域对行为的贡献的一种技术是重复经颅磁刺激（rTMS）。在本研究中，有十四名受试者在向左右背外侧前额叶皮层（DLPFC）接收一列rTMS之前和之后执行了停止信号任务。使用与事件抑制相关的事件相关电位（ERP）措施确定了rTMS的作用，在先前的研究中。左右DLPFC的刺激并不影响ERP的反应抑制措施。谨慎地解释了这一负面发现，但与最近的一项研究一致，该研究发现，相同区域的刺激对反应抑制的行为测量没有影响。

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