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首页> 外文期刊>Journal of stroke and cerebrovascular diseases: The official journal of National Stroke Association >Ischemic Stroke Subtype and Presence of Sleep-disordered Breathing: The BASIC Sleep Apnea Study
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Ischemic Stroke Subtype and Presence of Sleep-disordered Breathing: The BASIC Sleep Apnea Study

机译:缺血性中风亚型和睡眠呼吸障碍的存在:基本的睡眠呼吸暂停研究

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Background: Little is known about the prevalence of sleep-disordered breathing (SDB) across ischemic stroke subtypes. Given the important implications for SDB screening, we tested the association between SDB and ischemic stroke subtype in a population-based study. Methods: Within the Brain Attack Surveillance in Corpus Christi Project, ischemic stroke patients were offered SDB screening with the Apnea-Link Plus (n = 355). A neurologist assigned Trial of the ORG 10172 in Acute Stroke Treatment subtype (with an additional category for nonlacunar infarctions of unknown etiology) using hospital records. Unadjusted and adjusted (demographics, body mass index, National Institutes of Health Stroke Scale, diabetes, history of stroke/transient ischemic attack) logistic and linear regression models were used to test the association between subtype and SDB or apnea-hypopnea index (AHI). Results: Median age was 65%, and 55% were men; 59% were Mexican American. Median time from stroke onset to SDB screen was 13 days (interquartile range [IQR] 6, 21). Overall, 215 (61%) had SDB (AHI >= 10). Median AHI was 13 (IQR 6, 27). Prevalence of SDB by subtype was cardioembolism, 66%; large-artery atherosclerosis, 57%; small-vessel occlusion, 68%; other determined, 50%; undetermined etiology, 58%; and nonlacunar stroke of unknown etiology, 63%. Ischemic stroke subtype was not associated with SDB in unadjusted (P = .72) or adjusted models (P = .91) models. Ischemic stroke subtype was not associated with AHI in unadjusted (P = .41) or adjusted models (P = .62). Conclusions: In this population-based stroke surveillance study, ischemic stroke subtype was not associated with the presence or severity of SDB. Sleep-disordered breathing is likely to be present after ischemic stroke, and the subtype should not influence decisions about SDB screening.
机译:背景:关于缺血性中风亚型的睡眠呼吸障碍(SDB)的患病率知之甚少。鉴于对SDB筛查具有重要意义,我们在一项基于人群的研究中测试了SDB与缺血性卒中亚型之间的关联。方法:在Corpus Christi项目的脑部发作监测中,通过Apnea-Link Plus(n = 355)对缺血性卒中患者进行SDB筛查。一名神经科医生根据医院的记录分配了ORG 10172在急性中风治疗亚型中的试验(还有其他类别的病因不明的非腔隙性脑梗死)。使用未经调整和调整(人口统计学,体重指数,美国国立卫生研究院卒中量表,糖尿病,中风/短暂性脑缺血发作的历史)的逻辑和线性回归模型测试亚型与SDB或呼吸暂停低通气指数(AHI)之间的关联。结果:中位年龄为65%,男性为55%; 59%是墨西哥裔美国人。从中风发作到SDB筛查的中位时间为13天(四分位间距[IQR] 6、21)。总体而言,有215名(61%)患有SDB(AHI> = 10)。 AHI中位数为13(IQR 6,27)。 SDB亚型患病率为心脏栓塞,占66%;大动脉粥样硬化57%;小血管阻塞,占68%;其他确定的,50%;病因未定,58%;病因不明的非腔隙性中风占63%。在未经调整(P = .72)或经过调整的模型(P = .91)的模型中,缺血性卒中亚型与SDB无关。在未经调整(P = 0.41)或经过调整的模型(P = 0.62)中,缺血性卒中亚型与AHI无关。结论:在这项基于人群的中风监测研究中,缺血性中风亚型与SDB的存在或严重程度无关。缺血性中风后可能出现睡眠呼吸障碍,该亚型不应影响有关SDB筛查的决定。

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