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首页> 外文期刊>Journal of stroke and cerebrovascular diseases: The official journal of National Stroke Association >Characteristics of Sleep-Disordered Breathing in Etiologic Subtypes of Minor-to-Moderate Acute Ischemic Stroke
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Characteristics of Sleep-Disordered Breathing in Etiologic Subtypes of Minor-to-Moderate Acute Ischemic Stroke

机译：轻度至中度急性缺血性卒中病因亚型的睡眠呼吸障碍特征

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Background: Sleep-disordered breathing (SDB) is frequent in stroke patients. A strong association has been suggested between SDB and atrial fibrillation (AF). In this study, we evaluated the characteristics of SDB in etiologic subtypes of acute ischemic stroke. We also investigated the relationship between SDB and AF in acute ischemic stroke. Methods: We prospectively enrolled 72 patients with minor-to-moderate acute ischemic stroke. Clinical and laboratory characteristics of population were recorded on admission. SDB was assessed using standard polysomnography within 7 days after stroke onset. Results: Apnea-hypopnea index (AHI) in small-vessel strokes was significantly lower than that in large-artery atherosclerosis strokes (P = .031), cardioembolic strokes (P = .011), and strokes of other or unknown etiology (. 008). Desaturation index (DI) in small-vessel strokes was significantly lower than that in cardioembolic strokes and in large-artery strokes (P = .008, P = .035). Arousal index (AI) in large-artery strokes was significantly higher than that in small-vessel strokes (P = .013), cardioembolic strokes (P = .007), and strokes of other or unknown etiology (. 027). In a multivariate regression model were age (odds ratio [ OR], 1.083; 95% confidence interval [CI], 1.022-1.148; P = .007) and DI (OR, 1.037; 95% CI, 1.004-1.071; P = .026) the only significant variables independently associated with AF. Conclusions: We observed higher AHI, DI, and AI in large-artery strokes that may relate to more severe neurologic deficit in this subgroup. Age and DI were the only independent variables significantly associated with AF in acute ischemic stroke. Higher AHI and DI in cardioembolic strokes may thus mirror more frequent premorbid presence of SDB in patients with AF.
机译：背景：中风患者经常出现睡眠呼吸障碍（SDB）。已建议在SDB与房颤（AF）之间建立强关联。在这项研究中，我们评估了急性缺血性卒中病因亚型中SDB的特征。我们还研究了急性缺血性卒中中SDB和AF之间的关系。方法：我们前瞻性纳入了72例轻度至中度急性缺血性中风患者。入院时记录人群的临床和实验室特征。在卒中发作后7天内，使用标准的多导睡眠监测仪评估SDB。结果：小血管卒中的呼吸暂停低通气指数（AHI）明显低于大动脉粥样硬化卒中（P = .031），心脏栓塞性卒中（P = .011）和其他或未知病因的卒中（。 008）。小血管卒中的去饱和指数（DI）显着低于心脏栓塞性卒中和大动脉卒中（P = .008，P = .035）。大动脉卒中的唤醒指数（AI）显着高于小血管卒中（P = .013），心脏栓塞性卒中（P = .007）和其他或未知病因的卒中（。027）。在多元回归模型中，年龄（赔率[OR]为1.083; 95％置信区间[CI]为1.022-1.148; P = .007）和DI（OR为1.037; 95％CI为1.004-1.071; P = .026）与AF相关的唯一重要变量。结论：我们在大动脉卒中中观察到较高的AHI，DI和AI，可能与该亚组中更严重的神经功能缺损有关。在急性缺血性卒中中，年龄和DI是与房颤显着相关的唯一独立变量。因此，在心脏栓塞性卒中中，较高的AHI和DI可能反映了AF患者SDB病前更频繁地出现。

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