...
  • 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Journal of stroke and cerebrovascular diseases: The official journal of National Stroke Association >Intra-arterial Administration of Papaverine during Mechanical Thrombectomy for Acute Ischemic Stroke
【24h】

Intra-arterial Administration of Papaverine during Mechanical Thrombectomy for Acute Ischemic Stroke

机译：急性缺血性脑卒中机械血栓切除术中罂粟碱的动脉内给药。

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

Background: The use of stent retrievers for mechanical thrombectomy in acute ischemic stroke may induce significant vasospasm, which at the early phases of reperfusion may be crucial for rethrombosis of the recanalized vessel. We aimed to study whether the use of intra-arterial papaverine in selected cases of vasospasm was associated with improved cerebral perfusion, arterial reocclusion, or increased hemorrhagic complications. Methods: We retrospectively studied 9 consecutive patients with large artery acute occlusion, treated with stent retriever and intraarterial papaverine. Onset to administration of intravenous recombinant tissueplasminogen activator time, baseline National Institute of Health Stroke Scale, time to reperfusion, number of passes of the stent retriever, modified Rankin Scale score at discharge, postprocedural hemorrhage, onset to reperfusion time, papaverine dose, and thrombolysis in cerebral infarction grade were recorded in all patients. Results: After papaverine administration, the caliber of the infused arteries and their flow was increased in all cases. In none of the treated cases a reocclusion occurred after papaverine infusion. In one of the studied patients (11%), a parenchymal bleeding occurred 36 hours postoperatively. Conclusions: This small study suggests that intra-arterial infusion of papaverine for the treatment of cerebral vasospasm after mechanical thrombectomy in acute ischemic stroke is effective and safe.
机译：背景：在急性缺血性卒中中使用支架取血器进行机械血栓切除术可能会引起明显的血管痉挛，这在再灌注的早期可能对再通血管的血栓形成至关重要。我们旨在研究在选定的血管痉挛病例中使用动脉内罂粟碱是否与改善脑灌注，动脉再闭塞或出血并发症增加有关。方法：我们回顾性研究了9例连续的大动脉急性闭塞性患者，分别接受了支架取出器和动脉内罂粟碱治疗。开始使用静脉注射重组组织纤溶酶原激活物的时间，美国国立卫生研究院卒中量表的基线，再灌注时间，支架取回器的通过次数，出院时改良的Rankin量表评分，手术后出血，再灌注时间，罂粟碱剂量和溶栓治疗所有患者均记录脑梗死分级。结果：注射罂粟碱后，所有情况下输注动脉的口径和流量均增加。在所有治疗病例中，罂粟碱输注后均未发生再闭塞。在其中一位研究的患者（11％）中，在术后36小时发生了实质性出血。结论：这项小型研究表明，罂粟碱的动脉内输注治疗急性缺血性卒中机械血栓切除术后脑血管痉挛是有效和安全的。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号