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首页> 外文期刊>Journal of substance abuse treatment >Self-treatment: illicit buprenorphine use by opioid-dependent treatment seekers.
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Self-treatment: illicit buprenorphine use by opioid-dependent treatment seekers.

机译:自我治疗:阿片类药物依赖治疗者非法使用丁丙诺啡。

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摘要

Outpatient-based opioid treatment (OBOT) with buprenorphine is an important treatment for people with opioid dependence. No quantitative empirical research has examined rationales for use of illicit buprenorphine by U.S. opioid-dependent treatment seekers. The current study sequentially screened OBOT admissions (n = 129) during a 6-month period in 2009. This study had two stages: (a) a cross-sectional epidemiological analysis of new intakes and existing patients already receiving a legal OBOT prescription (n = 78) and (b) a prospective longitudinal cohort design that followed 76% of the initial participants for 3 months of treatment (n = 42). The primary aims were to establish 2009 prevalence rates for illicit buprenorphine use among people seeking OBOT treatment, to use quantitative methods to investigate reasons for this illicit use, and to examine the effect of OBOT treatment on illicit buprenorphine use behavior. These data demonstrate a decrease in illicit use when opioid-dependent treatment seekers gain access to legal prescriptions. These data also suggest that the use of illicit buprenorphine rarely represents an attempt to attain euphoria. Rather, illicit use is associated with attempted self-treatment of symptoms of opioid dependence, pain, and depression.
机译:以丁丙诺啡为基础的基于门诊病人的阿片类药物治疗(OBOT)是对阿片类药物依赖性患者的重要治疗方法。没有定量的经验研究检查了美国阿片类药物依赖治疗者使用非法丁丙诺啡的理由。当前的研究在2009年的6个月中对OBOT入院者进行了连续筛查(n = 129)。该研究分为两个阶段:(a)对新摄入量和已经接受合法OBOT处方的现有患者进行横断面流行病学分析(n = 78)和(b)采用前瞻性纵向队列设计,在76%的初始参与者中接受了3个月的治疗(n = 42)。主要目标是确定2009年寻求OBOT治疗的人群中非法使用丁丙诺啡的患病率,使用定量方法调查这种非法使用丁丙诺啡的原因,并研究OBOT治疗对非法丁丙诺啡使用行为的影响。这些数据表明,当阿片类药物依赖的寻求治疗者获得合法处方时,非法使用量将减少。这些数据还表明,非法丁丙诺啡的使用很少代表获得欣快感的尝试。而是,非法使用与试图自我治疗阿片类药物依赖性,疼痛和抑郁症状有关。

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