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首页> 外文期刊>Journal of the American Academy of Child and Adolescent Psychiatry >Risk for bipolar disorder is associated with face-processing deficits across emotions.
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Risk for bipolar disorder is associated with face-processing deficits across emotions.

机译:双相情感障碍的风险与跨情绪的面部加工缺陷有关。

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OBJECTIVE: Youths with euthymic bipolar disorder (BD) have a deficit in face-emotion labeling that is present across multiple emotions. Recent research indicates that youths at familial risk for BD, but without a history of mood disorder, also have a deficit in face-emotion labeling, suggesting that such impairments may be an endophenotype for BD. It is unclear whether this deficit in at-risk youths is present across all emotions or if the impairment presents initially as an emotion-specific dysfunction that then generalizes to other emotions as the symptoms of BD become manifest. METHOD: Thirty-seven patients with pediatric BD, 25 unaffected children with a first-degree relative with BD, and 36 typically developing youths were administered the Emotional Expression Multimorph Task, a computerized behavioral task, which presents gradations of facial emotions from 100% neutrality to 100% emotional expression (happiness, surprise, fear, sadness, anger, and disgust). RESULTS: Repeated-measures analysis of covariance revealed that, compared with the control youths, the patients and the at-risk youths required significantly more intense emotional information to identify and correctly label face emotions. The patients with BD and the at-risk youths did not differ from each other. Group-by-emotion interactions were not significant, indicating that the group effects did not differ based on the facial emotion. CONCLUSIONS: The youths at risk for BD demonstrate nonspecific deficits in face-emotion recognition, similar to patients with the illness. Further research is needed to determine whether such deficits meet all the criteria for an endophenotype.
机译:目的:患有正常性双相情感障碍(BD)的青年人的面部表情标签存在缺陷,并且存在多种情感。最近的研究表明,有家族性BD病风险但没有情绪障碍史的青年人的面部表情标签也有缺陷,这表明这种障碍可能是BD的内表型。目前尚不清楚在所有情绪中是否都存在这种处于危险中的青年人的赤字,或者这种障碍最初是否表现为特定于情绪的功能障碍,然后随着BD症状的表现而泛滥成其他情绪。方法:对37名小儿BD患者,25名未患儿,患有BD的一级亲属和36名典型的发育中的青年进行了情感表达多形体任务,这是一种计算机化的行为任务,可从100%中性显示面部表情的分级100%的情感表达(幸福,惊讶,恐惧,悲伤,愤怒和厌恶)。结果:协方差的重复测量分析显示,与对照组的年轻人相比,患者和处于危险中的年轻人需要更强烈的情绪信息来识别和正确标记面部表情。 BD患者和高危青少年之间没有差异。逐组情感的交互作用不显着,表明基于面部表情的组效果没有差异。结论:患BD的年轻人表现出与面部疾病相似的面部表情识别方面的非特异性缺陷。需要进一步的研究来确定这种缺陷是否满足内表型的所有标准。

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