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首页> 外文期刊>Journal of the International Neuropsychological Society: JINS >Neuropsychology and clinical neuroscience of persistent post-concussive syndrome.
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Neuropsychology and clinical neuroscience of persistent post-concussive syndrome.

机译：持续性脑震荡综合症的神经心理学和临床神经科学。

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摘要

On the mild end of the acquired brain injury spectrum, the terms concussion and mild traumatic brain injury (mTBI) have been used interchangeably, where persistent post-concussive syndrome (PPCS) has been a label given when symptoms persist for more than three months post-concussion. Whereas a brief history of concussion research is overviewed, the focus of this review is on the current status of PPCS as a clinical entity from the perspective of recent advances in the biomechanical modeling of concussion in human and animal studies, particularly directed at a better understanding of the neuropathology associated with concussion. These studies implicate common regions of injury, including the upper brainstem, base of the frontal lobe, hypothalamic-pituitary axis, medial temporal lobe, fornix, and corpus callosum. Limitations of current neuropsychological techniques for the clinical assessment of memory and executive function are explored and recommendations for improved research designs offered, that may enhance the study of long-term neuropsychological sequelae of concussion.
机译：在获得性脑损伤谱的轻度末端，术语脑震荡和轻度创伤性脑损伤（mTBI）可以互换使用，其中当症状持续超过三个月后，持续性脑震荡后综合征（PPCS）被标记为脑震荡。尽管概述了脑震荡研究的简要历史，但本综述的重点是从人和动物研究中脑震荡的生物力学建模的最新进展的角度出发，重点探讨PPCS作为临床实体的当前状况，尤其是为了更好地理解脑震荡相关的神经病理学这些研究暗示了常见的损伤区域，包括上脑干，额叶基部，下丘脑-垂体轴，颞中叶，穹ni和call体。探索了当前用于记忆和执行功能临床评估的神经心理学技术的局限性，并提出了改进研究设计的建议，这些研究可能会增强脑震荡的长期神经心理学后遗症的研究。

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