Synthesis and biological evaluatiion of 3-aryl-2-(2-chloro-7-methoxyquinolin-3-yl)-4-thiazolidinones

Ranjan Khunt; Neela Datta; Fatema Bharmal; A. R. Parikh

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Synthesis and biological evaluatiion of 3-aryl-2-(2-chloro-7-methoxyquinolin-3-yl)-4-thiazolidinones

机译：3-芳基-2-（2-氯-7-甲氧基喹啉-3-基）-4-噻唑烷酮的合成及生物评价

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3-Aryl-2-(2-chloro-7-methoxyquinolin-3-yl)-4-thiazolidinones (3a-m, 4a-m) have been synthesised by the condensation of thioglycolic acid/thiolactic acid with N-aryl-(2-chloro-7-methoxyuinolin-3-yl)azomethine (2a-m) which in turn are prepared from arylamine and 2-chloro-7-methoxyquinoline-3-carboxaldehyde (1). The products have been evaluated for their antibacterial and antifungal activities.

机译：通过将巯基乙酸/巯基乳酸与N-芳基-（-）缩合合成了3-芳基-2-（2-氯-7-甲氧基喹啉-3-基）-4-噻唑烷酮（3a-m，4a-m）然后由芳基胺和2-氯-7-甲氧基喹啉-3-甲醛（1）制得2-氯-7-甲氧基尿苷-3-基）偶氮甲碱（2a-m）。已对产品的抗菌和抗真菌活性进行了评估。

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《Journal of the Indian Chemical Society》 |2001年第1期|共2页
作者
Ranjan Khunt; Neela Datta; Fatema Bharmal; A. R. Parikh;
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1. Synthesis and biological evaluatiion of 3-aryl-2-(2-chloro-7-methoxyquinolin-3-yl)-4-thiazolidinones [J] . Ranjan Khunt, Neela Datta, Fatema Bharmal, Journal of the Indian Chemical Society . 2001,第1期

机译：3-芳基-2-（2-氯-7-甲氧基喹啉-3-基）-4-噻唑烷酮的合成及生物评价
2. 4-Thiazolidinone coumarin derivatives as two-component NS2B/NS3 DENV flavivirus serine protease inhibitors: synthesis, molecular docking, biological evaluation and structure–activity relationship studies [J] . Samina Khan Yusufzai, Hasnah Osman, Mohammad Shaheen Khan, Chemistry central journal . 2018,第1期

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3. Synthesis and Biological Evaluation of 4-thiazolidinone Derivatives [J] . Kathale SV, Bhandarkar SE Der Pharma Chemica: journal for medicinal chemistry, pharmaceutical chemistry and computational chemistry . 2017,第13期

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Synthesis and biological evaluatiion of 3-aryl-2-(2-chloro-7-methoxyquinolin-3-yl)-4-thiazolidinones

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