Synthesis and antimicrobial elucidation of [1,2,4]-triazoIe-3-thione derivatives

D. R. Godhani; A. M. Sanghani; D. B. Sanja

首页> 外文期刊>Journal of the Indian Chemical Society >Synthesis and antimicrobial elucidation of [1,2,4]-triazoIe-3-thione derivatives

【24h】

Synthesis and antimicrobial elucidation of [1,2,4]-triazoIe-3-thione derivatives

机译：[1,2,4]-三唑基-3-硫酮衍生物的合成与抗菌研究

获取原文

获取原文并翻译 | 示例

掌桥外文数据库（机构版） >>

开具论文收录证明 >>

文献代查 >>

页面导航

摘要
著录项
相似文献
相关主题

摘要

4-Nitro benzoyl isothiocyanate (1) is prepared by a reaction of 4-nitro benzoyl chloride and ammonium isothiocyanate. Compound 1 reacts with phenyl hydrazine in the presence of acetone to form 5-(4-nitrophenyl)-1-phenyI-1H-1,2,4-triazole-3(2H)-thione (2). Compounds 2 on reaction with formaldehyde and different aromatic amines in 1,4-dioxane yielded 2-(substituted-amino)methyl-5-(4-nitrophenyl)-1-phenyl-1H-1,2,4-triazole-3(2H)-thione (3a-j) respectively. The synthesized compound 3a-j were screened for their antibacterial and antifungal activities and characterized by spectral techniques like IR and NMR.

机译：4-硝基苯甲酰异硫氰酸酯（1）是通过4-硝基苯甲酰氯与异硫氰酸铵反应制得的。化合物1在丙酮存在下与苯肼反应形成5-（4-硝基苯基）-1-苯基-1H-1,2,4-三唑-3（2H）-硫酮（2）。与甲醛和不同的芳香胺在1,4-二恶烷中反应的化合物2生成2-（取代的氨基）甲基-5-（4-硝基苯基）-1-苯基-1H-1,2,4-三唑-3（ 2H）-硫酮（3a-j）。筛选合成的化合物3a-j的抗菌和抗真菌活性，并通过光谱技术（例如IR和NMR）进行表征。

著录项

来源
《Journal of the Indian Chemical Society》 |2012年第7期|共4页
作者
D. R. Godhani; A. M. Sanghani; D. B. Sanja;
展开▼
作者单位

展开▼
收录信息
原文格式 PDF
正文语种 eng
中图分类化学;
关键词
Acid chloride; aryl hydrazine; ammonium thiocyanate; 1; 2; 4-triazole-3-thione; Mannich reaction; mercapto-1; 2; 4-triazole.;

机译：酰氯;芳基肼;硫氰酸铵;1;2;4-三唑-3-硫酮;曼尼希反应;巯基-1;2;4-三唑;

相似文献

外文文献
中文文献
专利

1. Synthesis and antimicrobial elucidation of [1,2,4]-triazoIe-3-thione derivatives [J] . D. R. Godhani, A. M. Sanghani, D. B. Sanja Journal of the Indian Chemical Society . 2012,第7期

机译：[1,2,4]-三唑基-3-硫酮衍生物的合成与抗菌研究
2. Synthesis, reactions, and antimicrobial activity of some novel pyrazolo[3,4-d]pyrimidine, pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidine, and pyrazolo[4,3-e][1,2,4]triazolo[3,4-c]pyrimidine derivatives [J] . Hassaneen Hamdi M., Saleh Fatma M., Abdallah Tayseer A., Journal of Heterocyclic Chemistry: The International Journal of Heterocyclic Chemistry . 2020,第2期

机译：一些新型吡唑的合成，反应和抗微生物活性[3,4-D]嘧啶，吡唑啉[4,3-e] [1,2,4]三唑唑[1,5-C]嘧啶和吡唑[4， 3-e] [1,2,4]三唑唑[3,4-C]嘧啶衍生物
3. SYNTHESIS, CHARACTERIZATION AND ANTIMICROBIAL EVALUATION OF SOME NOVEL FUSED PYRIMIDO[1,2-b][1,2,4]TRIAZINE, TRIAZINO[2,3-a]QUINAZOLINE AND IMIDAZO[1,2-b][1,2,4]TRIAZINE DERIVATIVES [J] . Mohamed Khaled S., El-Sayed Elsherbiny H. Heterocycles: An International Journal for Reviews and Communications in Heterocyclic Chemistry . 2018,第11期

机译：一些新型熔融嘧啶的合成，表征和抗微生物评价[1,2- b] [1,2,4]三嗪，三嗪[2,3-A]喹唑啉和咪唑[1,2-B] [1,2， 4]三嗪衍生物
4. MICROWAVE ASSISTED SYNTHESIS OF SOME NEW 3-(4-AMINO-5-THIOXO-1,2,4-TRIAZOLE-3-YL)METHYL-2(3H)-BENZOXAZOLONE DERIVATIVES AS ANTIMICROBIAL AGENTS [C] . Solen URLU, Tijen ONKOL, M. Fethi SAHIN European Symposium on Organic Chemistry . 2009

机译：微波辅助合成一些新的3 - （4-氨基-5-硫代-1,2,4-三唑-3-基）甲基 -2（3H） - 低恶唑酮衍生物作为抗微生物剂
5. Synthesis of potent analogs of the antimalarial 1,2,4-trioxane natural product artemisinin, and, mechanistic studies directed towards elucidation of the mechanism(s) of antimalarial action of artemisinin and its 1,2,4-trioxane analogs. [D] . Cumming, Jared Nathaniel. 1998

机译：合成抗疟疾的1,2,4-三恶烷天然产物青蒿素的有效类似物，以及旨在阐明青蒿素及其1,2,4-三恶烷类似物的抗疟作用机理的机理研究。
6. New Series of Thiazole Derivatives: Synthesis Structural Elucidation Antimicrobial Activity Molecular Modeling and MOE Docking [O] . Ismail Althagafi, Nashwa El-Metwaly, Thoraya A. Farghaly 2019

机译：噻唑衍生物的新系列：合成结构阐明抗菌活性分子模型和教育部对接。
7. New Series of Thiazole Derivatives: Synthesis, Structural Elucidation, Antimicrobial Activity, Molecular Modeling and MOE Docking [O] . Ismail Althagafi, Nashwa El-Metwaly, Thoraya A. Farghaly 2019

机译：新系列噻唑衍生物：合成，结构阐明，抗菌活性，分子造型和MOE对接

Synthesis and antimicrobial elucidation of [1,2,4]-triazoIe-3-thione derivatives

摘要

著录项

相似文献

相关主题

期刊订阅