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What does a common channel for electrolytes and non-electrolytes in the sperm mean?

机译:精子中的电解质和非电解质的通用通道是什么意思?

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摘要

Cell volume is central to osmoregulation in intact cells. Bovine spermatozoa, as also other mammalian spermatozoa, exhibit a very rapid regulatory volume decrease (RVD) when exposed to hypotonic saline media. This response, fastest known in animal cells, is mediated by a putative potassium channel which the pharmacological properties of a conventional channel and yet admits both electrolytes and non-electrolytes. The evolutionary basis and functional role of this conserved quinine-sensitive channel in mammalian sperm could offer hitherto unexplored facets of the link(s) between ecology and reproduction. (C) 2000 Academic Press. [References: 55]
机译:细胞体积是完整细胞渗透调节的关键。牛精子以及其他哺乳动物的精子,暴露于低渗盐溶液中时,会表现出非常快速的调节体积减少(RVD)。这种反应是动物细胞中已知最快的,是由推定的钾通道介导的,该通道具有常规通道的药理特性,但同时允许电解质和非电解质。该保守的奎宁敏感通道在哺乳动物精子中的进化基础和功能作用可为生态学与生殖之间的联系提供迄今尚未探索的方面。 (C)2000学术出版社。 [参考:55]

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