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首页> 外文期刊>Journal of Theoretical Biology >A competition model between Pseudomonas fluorescens and pathogens via iron chelation.
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A competition model between Pseudomonas fluorescens and pathogens via iron chelation.

机译：荧光假单胞菌与病原体通过铁螯合的竞争模型。

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摘要

In this study we present a competition model between a non-chelator (e.g. pathogen) microorganism and an iron chelator microorganism (e.g. Pseudomonas fluorescens). This latter is a beneficial bacteria that can inhibit the growth of the non-chelator through its iron chelating capability. This phenomena of iron chelation is shown to prevent the pathogen from proliferating to numbers capable of causing disease. A mathematical model is formulated and used to study this competition. The model proposes a new and simple conceptual explanation of interactions. It is a nonlinear system of ordinary differential equations. A qualitative analysis of the model for the batch case (no inflow or outflow from the system) is carried out and the global behavior of the model variables is studied. For the chemostat case, the equilibrium points were derived and their stability was performed through extensive numerical simulations. It is found that iron chelation is able to control the non-chelator microorganism growth under a wide range of conditions.
机译：在这项研究中，我们提出了非螯合剂（例如病原体）微生物和铁螯合剂微生物（例如荧光假单胞菌）之间的竞争模型。后者是有益的细菌，可以通过其铁螯合能力抑制非螯合剂的生长。已显示出这种铁螯合现象可防止病原体扩散到能够引起疾病的数量。制定了数学模型并将其用于研究这场比赛。该模型提出了一种新的，简单的交互概念说明。它是一个常微分方程的非线性系统。对批次情况下的模型进行了定性分析（没有流入或流出系统），并且研究了模型变量的全局行为。对于化学稳定剂，通过广泛的数值模拟得出平衡点，并进行稳定性计算。发现铁螯合能够在广泛的条件下控制非螯合剂微生物的生长。

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