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首页> 外文期刊>Journal of Veterinary Diagnostic Investigation >Malignant mesothelioma of the tunica vaginalis testis in a dog: histological and immunohistochemical characterization.
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Malignant mesothelioma of the tunica vaginalis testis in a dog: histological and immunohistochemical characterization.

机译：犬阴道睾丸的恶性间皮瘤：组织学和免疫组化特征。

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摘要

Histologic and immunohistochemical features of a malignant mesothelioma of the testicular tunica vaginalis in a 9-year-old male mixed-breed dog are reported. The dog had a large scrotal swelling determined by ultrasonography to be a heterogeneous irregular mass characterized by a mixed echogenic pattern and located in the left vaginal canal of the testis. Histologically, the neoplasm was nodular, was poorly demarcated, and consisted of pleomorphic cells that were associated with a significant desmoplastic reaction. By immunohistochemistry, neoplastic cells stained positively for cytokeratin and vimentin and were immunoreactive with an antimesothelial cell monoclonal antibody. Malignant mesotheliomas of tunica vaginalis testis are rare in mammalian species, including dogs.
机译：据报道，在一只9岁的雄性混种狗中，阴道睾丸恶性间皮瘤的组织学和免疫组化特征。这只狗的阴囊肿大，经超声检查发现是异质性不规则肿块，其特征是混合了回声模式，位于睾丸的左阴道道。在组织学上，肿瘤呈结节状，分界差，由多形细胞组成，这些细胞与明显的增塑反应有关。通过免疫组织化学，肿瘤细胞的细胞角蛋白和波形蛋白呈阳性染色，并与抗间皮细胞单克隆抗体发生免疫反应。阴道膜睾丸的恶性间皮瘤在包括狗在内的哺乳动物中很少见。

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