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On the Origins of Species: Does Evolution Repeat Itself in Polyploid Populations of Independent Origin?

机译:关于物种起源:进化是否会在独立起源的多倍体种群中重演?

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Multiple origins of the same polyploid species pose the question: Does evolution repeat itself in these independently formed lineages? Tragopogon is a unique evolutionary model for the study of recent and recurrent allopolyploidy. The allotetraploids T. mirus (T. dubius x T. porrifolius) and T. miscellus (T. dubius x T. pratensis) formed repeatedly following the introduction of three diploids to the United States. Concerted evolution has consistently occurred in the same direction (resulting in loss of T. dubius rDNA copies). Both allotetraploids exhibit homeolog loss, with the same genes consistently showing loss, and homeologs of T. dubius preferentially lost in both allotetraploids. We have also documented repeated patterns of tissue-specific silencing in multiple populations of T. miscellus. Hence, some aspects of genome evolution may be "hardwired," although the general pattern of loss is stochastic within any given population. On the basis of the study of F_1 hybrids and synthetics, duplicate gene loss and silencing do not occur immediately following hybridization or polyploidization, but gradually and haphazardly. Genomic approaches permit analysis of hundreds of loci to assess the frequency of homeolog loss and changes in gene expression. This methodology is particularly promising for groups such as Tragopogon for which limited genetic and genomic resources are available.
机译:同一多倍体物种的多个起源提出了一个问题:进化是否在这些独立形成的谱系中重复出现? tragopogon是用于研究近期和复发同种多倍体的独特进化模型。在将三种二倍体引入美国后,异源四倍体T. mirus(T. dubius x porrifolius)和T. miscellus(T. dubius x T. pratensis)反复形成。一致的进化一直沿相同的方向发生(导致杜比螺旋体rDNA拷贝丢失)。两种异源四倍体均显示同源异型丢失,相同的基因始终显示出缺失,而两个异源四倍体中均优先缺失杜比螺旋杆菌的同源物。我们还记录了在多个T. miscellus种群中组织特异性沉默的重复模式。因此,基因组进化的某些方面可能是“硬连线的”,尽管在任何给定种群中,一般的丢失模式都是随机的。根据对F_1杂种和合成物的研究,杂交或多倍体化后不会立即发生重复的基因丢失和沉默,而是逐渐而偶然地发生。基因组方法可分析数百个基因座,以评估同源同源物丢失的频率和基因表达的变化。这种方法对于像Tragopogon这样的群体来说是特别有前途的,因为该群体的遗传和基因组资源有限。

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