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首页> 外文期刊>Journal of Surgical Oncology >Bile cultures: a guide to infectious complications after pancreaticoduodenectomy.
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Bile cultures: a guide to infectious complications after pancreaticoduodenectomy.

机译：胆汁培养：胰十二指肠切除术后感染并发症的指南。

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BACKGROUND: The aim of this study was to evaluate the utility of intraoperative bile cultures on the outcome of patients undergoing pancreaticoduodenectomy. STUDY DESIGN: A review of a hepato-pancreato-biliary database was performed to identify all patients who had a pancreaticoduodenectomy from 1/1998 to 8/2008. RESULTS: Two hundred twenty-eight patients were evaluated, with preoperative biliary stenting performed in 129 out of 229 patients (57%), with 63/129(49%) had bile cultures taken intraoperatively, 39/129(30%) having positive bile cultures. Neither preoperative biliary stenting (incidence of complication: 54% with stent vs. 51% without, P = 0.9) nor positive bile culture (incidence of complication: 54% with positive bile culture vs. 53% without, P = 0.9) were predictors of overall complications. Length of operating time, length of hospital stay, blood loss, blood transfusion, and severity of complications were similar in the group with and without stent. There were 19 different organisms identified with not a single species was a statistically significant predictor of neither severity of complication nor increased length of stay. CONCLUSIONS: Preoperative biliary stenting correlates with similar rate of biliary infections, however, intraoperative bile culture allows for early appropriate antibiotic use, which maintains a similar morbidity and infectious incidence as in patients without stents.
机译：背景：本研究的目的是评估术中胆汁培养对胰十二指肠切除术患者预后的实用性。研究设计：回顾了肝胰胆管数据库，以鉴定从1/1998到8/2008接受胰十二指肠切除术的所有患者。结果：对228例患者进行了评估，其中229例患者中有129例进行了术前胆道支架置入术（57％），术中进行胆汁培养的占63/129（49％），阳性的占39/129（30％）胆汁文化。术前胆道内支架置入术（并发症发生率：支架置入率为54％，无支架置入发生率为51％，P = 0.9）和胆汁培养阳性（并发症发生率：置入胆汁置入为阳性率分别为54％，无胆管造血术的发生率为53％，P = 0.9）均不是预测因素总体并发症。有支架和无支架组的手术时间，住院时间，失血，输血和并发症的严重程度相似。有19种不同的生物体被鉴定为不是单一物种，这既不是并发症严重程度也不是住院时间增加的统计显着预测因子。结论：术前胆道支架置入术与相似的胆道感染率相关，但是，术中胆汁培养可及早适当使用抗生素，与未置入支架的患者保持相似的发病率和感染率。

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