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首页> 外文期刊>Journal of Surgical Oncology >Review of the clinical, histological, and molecular aspects of pancreatic endocrine neoplasms.
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Review of the clinical, histological, and molecular aspects of pancreatic endocrine neoplasms.

机译:回顾胰腺内分泌肿瘤的临床,组织学和分子方面。

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摘要

Pancreatic endocrine neoplasms (PENs) are rare tumors, and little is known about their genetic and chromosomal alterations. Elucidation of the molecular events involved in PEN carcinogenesis has been hindered by the fact that PENs have been considered a single disease entity. The emergence of novel molecular characterization strategies has, however, made it apparent that these lesions exhibit diverse molecular fingerprints, which will facilitate the precise delineation of PEN prognosis, histopathology, and carcinogenesis. J. Surg. Oncol. 2002;81:45-53.
机译:胰腺内分泌肿瘤(PEN)是罕见的肿瘤,对其遗传和染色体改变知之甚少。由于PEN被认为是单一疾病实体,因此阻碍了PEN致癌分子机制的阐明。然而,新的分子表征策略的出现使这些病变表现出了多样的分子指纹,这将有助于PEN预后,组织病理学和致癌作用的精确描绘。 J. Surg。 Oncol。 2002; 81:45-53。

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