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首页> 外文期刊>Comparative Medicine >Efficacy of Antibiotic-Impregnated Polymethylmethacrylate Beads in a Rhesus Macaque (Macaca mulatta) with Osteomyelitis
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Efficacy of Antibiotic-Impregnated Polymethylmethacrylate Beads in a Rhesus Macaque (Macaca mulatta) with Osteomyelitis

机译：恒河猴猕猴对骨髓炎的抗菌素浸渍的聚甲基丙烯酸甲酯微珠的功效

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摘要

Here we describe the successful surgical implementation of antibiotic-impregnated polymethylmethacrylate beads in a rhesus macaque (Macaca mulatto) with marked osteomyelitis. The macaque presented to the veterinary clinic with grossly contaminated bite wounds in the left ankle secondary to conspecific trauma. Radiographic findings were highly suggestive of osteomyelitis. Additional differential diagnoses included bony infarct, fracture, and cellulitis. In light of the location of the lesion and extensive tissue trauma, the animal had a poor prognosis. Systemic, broad-spectrum antibiotics were instituted. After 2 wk of care, lesions did riot respond to empirical therapies. On consultation, a veterinary orthopedic surgeon at another facility recommended placement of antibiotic-impregnated polymethylmethacrylate beads at the sites of osteomyelitis. The animal underwent minor surgery in which beads were introduced into the wound. The monkey had a positive response to therapy. The animal regained full function and was returned to outdoor social. housing. Veterinarians are encouraged to consider using antibiotic-impregnated polymethylmethacrylate beads when treating osteomyelitis in other nonhuman primates and in other traditional laboratory animal species.
机译：在这里，我们描述了在猕猴（猕猴）中患有明显的骨髓炎的抗生素浸渍的聚甲基丙烯酸甲酯微珠的成功外科手术实施。猕猴出现在兽医诊所，继发于特定的外伤后，左脚踝严重受咬咬伤。影像学检查结果高度提示骨髓炎。其他鉴别诊断包括骨梗塞，骨折和蜂窝织炎。鉴于病变的位置和广泛的组织创伤，该动物的预后较差。建立了系统的广谱抗生素。经过2周的护理，病灶对经验疗法没有反应。经咨询，另一家机构的兽医骨科医生建议在骨髓炎的部位放置浸有抗生素的聚甲基丙烯酸甲酯微珠。对该动物进行了小手术，其中将珠子引入伤口。猴子对治疗有积极的反应。该动物恢复了全部功能，并重返户外活动。住房。鼓励兽医在治疗其他非人类灵长类动物和其他传统实验动物物种的骨髓炎时考虑使用抗生素浸渍的聚甲基丙烯酸甲酯微珠。

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