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Biorepository Proficiency Testing for the Quality Control of Biospecimens for the Global Biobanking Community

机译:用于全球生物银行界生物标本质量控制的生物存储库能力测试

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摘要

Until now, proficiency testing programs have not existed for the quality assessment of biospecimens that are used in basic, translational, and clinical research studies, yet the discovery, validation, and clinical evaluation of bio-markers necessary for the advancement of global health depend upon the availability of a large number of standardized specimens. To meet this void, ISBER has launched a biorepository Proficiency Testing (PT) Program in partnership with the Integrated Biobank of Luxembourg (IBBL). The ISBER PT Program belongs to the category of inter-laboratory comparison "schemes" involving simultaneous participation of biorepository laboratories located in different countries. Randomly selected aliquots from a source material prepared at IBBL (the test items) are being distributed and tested concurrently by all registered participants. After the completion of the testing, the participants' results will be returned to the Proficiency Testing provider (ISBER) and compared with the assigned value(s) derived from the reference laboratories to give an indication of the performance of the individual participants and of the group as a whole.
机译:迄今为止,还没有用于基础,转化和临床研究的生物样本质量评估的能力验证程序,但是,对促进全球健康的生物标记物的发现,验证和临床评估取决于大量标准化标本的可用性。为了弥补这一空白,ISBER与卢森堡综合生物银行(IBBL)合作启动了一个生物资源库能力测试(PT)计划。 ISBER PT计划属于实验室间比较“计划”的类别,该计划涉及同时参与位于不同国家/地区的生物储存库实验室。从IBBL准备的原始材料(测试项目)中随机选择的等分试样将由所有注册参与者同时分发和测试。测试完成后,参与者的结果将返回给能力测试提供者(ISBER),并与参考实验室得出的分配值进行比较,以表明单个参与者和参与者的表现。组整体。

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