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Myopia and the long-term incidence of cataract and cataract surgery: The Blue Mountains Eye Study

机译:近视眼与白内障的长期发病率及白内障手术:《蓝山眼》研究

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Background: To assess the association between refractive errors and the 10-year incidence of cataract and cataract surgery. Design: Population-based prospective study. Participants: Three thousand six hundred fifty-four persons aged 49+ years living in a well-defined geographical region were examined at baseli≠ 2564 were re-examined after 5 and/or 10 years. Methods: Baseline refractive error was measured using autorefraction with subjective refinement. Lens photographs were taken at each visit and assessed using the Wisconsin Cataract Grading System. Main Outcome Measures: Long-term incidence of cataract and cataract surgery. Results: Compared with emmetropia, high myopia was associated with increased incidence of nuclear cataract (adjusted odds ratio 3.01, 95% confidence intervals 1.35-6.71). Low (odds ratio 1.86, confidence interval 1.03-3.35) and high myopia (odds ratio 7.80, confidence interval 3.51-17.35) were significantly associated with higher incidence of posterior subcapsular cataract. Low, moderate and high myopia were associated with increased incidence of cataract surgery (odds ratio 2.54, confidence interval 1.76-3.68; odds ratio 2.61, confidence interval 1.45-4.69; and odds ratio 4.81, confidence interval 2.33-9.93, respectively). Either any (odds ratio 1.35, confidence interval 1.08-1.69) or moderate hyperopia (odds ratio 1.76, confidence interval 1.32-2.34) was associated with increased incidence of nuclear cataract. Conclusion: Our longitudinal study confirms the association between myopia and an increased risk of nuclear and posterior subcapsular cataract. It also suggests that hyperopia may increase the risk of nuclear cataract.
机译:背景:评估屈光不正与白内障和白内障手术十年发病率之间的关联。设计:基于人群的前瞻性研究。参与者:在明确定义的地理区域中,有3,654位年龄在49岁以上的人在baseli≠2564接受了检查,他们在5年和/或10年后进行了重新检查。方法:采用主屈光度自折射测量基线屈光不正。每次访问都拍摄镜头照片,并使用威斯康星州白内障评分系统进行评估。主要结果指标:白内障的长期发病率和白内障手术。结果:与正视眼相比,高度近视与核性白内障发生率增加相关(校正比值比3.01,95%置信区间1.35-6.71)。低度(奇数比1.86,置信区间1.03-3.35)和高度近视(奇数比7.80,置信区间3.51-17.35)与后囊性白内障的发生率较高显着相关。低度,中度和高度近视与白内障手术的发生率增加相关(分别为:优势比2.54,置信区间1.76-3.68;优势比2.61,置信区间1.45-4.69;优势比4.81,置信区间2.33-9.93)。任何一种(几率1.35,置信区间1.08-1.69)或中度远视(几率1.76,置信区间1.32-2.34)都与核性白内障的发生率增加有关。结论:我们的纵向研究证实了近视与核和后囊后白内障风险增加之间的关联。这也表明远视可能会增加核性白内障的风险。

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