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首页> 外文期刊>Clinical and laboratory haematology >Aspergillus brain abscess in a patient with acute myeloid leukaemia successfully treated with voriconazole.
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Aspergillus brain abscess in a patient with acute myeloid leukaemia successfully treated with voriconazole.

机译:伏立康唑成功治疗了急性髓性白血病患者的曲霉脑脓肿。

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摘要

Cerebral aspergillosis is associated with very high mortality in immunocompromised hosts. Conventional antifungal agents like amphotericin-B and itraconazole are almost ineffective in cerebral aspergillosis. Newer azoles have been shown to penetrate the blood, cerebrospinal fluid barrier and achieve effective fungicidal concentrations. These newer azoles may change the outlook of this fatal condition. We report here a patient with cerebral aspergillosis who was successfully treated with voriconazole.
机译:在免疫功能低下的宿主中,脑曲霉病的死亡率很高。常规的抗真菌药,如两性霉素B和伊曲康唑,对脑曲霉病几乎无效。新型唑类药物已显示可渗透血液,脑脊液屏障并达到有效的杀真菌浓度。这些新型的唑类可能会改变这种致命状况的面貌。我们在这里报告了成功使用伏立康唑治疗的脑曲霉病患者。

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