Effect of electrical stimulation of sciatic nerve on synaptic plasticity of spinal dorsal horn and spinal c-fos expression in neonatal, juvenile and adult rats.

Jiang Wu; Qisheng Hu; Deying Huang; Xueling Chen; Jie Chen

首页> 外文期刊>Brain research >Effect of electrical stimulation of sciatic nerve on synaptic plasticity of spinal dorsal horn and spinal c-fos expression in neonatal, juvenile and adult rats.

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Effect of electrical stimulation of sciatic nerve on synaptic plasticity of spinal dorsal horn and spinal c-fos expression in neonatal, juvenile and adult rats.

机译：坐骨神经电刺激对新生，幼年和成年大鼠脊髓背角突触可塑性和脊髓c-fos表达的影响。

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To explore the response to nociceptive stimuli in spinal cord of immature rat and observe the electrical stimulation of the sciatic nerve on synaptic plasticity of the spinal dorsal horn and spinal c-fos expression in rats of different ages, MK-801 was added to the spinal cord of rats, and the resulting changes in field potential as well as c-fos expression were recorded. LTP in neonatal rats was mainly evoked by A-type nerve fibers, whereas LTP in juvenile and adult rats was mainly evoked by C-type nerve fibers. C-fos expression was significantly increased in the superficial and deep layers of the spinal dorsal horn and in the ventral horn in neonatal rats indicating that the pain signal changed with age.

机译：为了探讨未成熟大鼠脊髓对伤害感受性刺激的反应，并观察坐骨神经对不同年龄大鼠脊髓背角突触可塑性和脊髓c-fos表达的电刺激，在脊髓中添加了MK-801记录大鼠的脊髓，并记录由此产生的场势以及c-fos表达的变化。新生大鼠的LTP主要由A型神经纤维引起，而幼年和成年大鼠的LTP主要由C型神经纤维引起。新生大鼠的脊髓背角的浅层和深层以及腹角的C-fos表达显着增加，表明疼痛信号随年龄而变化。

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《Brain research》 |2012年第null期|共9页
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Jiang Wu; Qisheng Hu; Deying Huang; Xueling Chen; Jie Chen;
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1. Effect of electrical stimulation of sciatic nerve on synaptic plasticity of spinal dorsal horn and spinal c-fos expression in neonatal, juvenile and adult rats. [J] . Jiang Wu, Qisheng Hu, Deying Huang, Brain research . 2012,第Null期

机译：坐骨神经电刺激对新生，幼年和成年大鼠脊髓背角突触可塑性和脊髓c-fos表达的影响。
2. Compensatory projection of primary nociceptors and c-fos induction in the spinal dorsal horn following neonatal sciatic nerve lesion. [J] . Sugimoto T, Li YL, Kishimoto H, Experimental Neurology . 2000,第2期

机译：新生儿坐骨神经病变后脊髓背角的主要伤害感受器和c-fos诱导的补偿性投影。
3. Plasticity in expression of the glutamate transporters GLT-1 and GLAST in spinal dorsal horn glial cells following partial sciatic nerve ligation [J] . Wen-Jun Xin, Han-Rong Weng, Patrick M Dougherty Molecular pain . 2009,第1期

机译：坐骨神经部分结扎后脊髓背角神经胶质细胞谷氨酸转运蛋白GLT-1和GLAST表达的可塑性
4. Cellular Mechanisms for the Enhancement by Bee Venom Melittin of GABAergic and Glycinergic Inhibitory Synaptic Transmission in Adult Rat Spinal Dorsal Horn Neurons [C] . Tao Liu, Tsugumi Fujita, Hai-Yuan Yue Japanese peptide symposium . 2010

机译：大鼠脊髓背角神经元的甘草能和甘油池抑制突触突触突出的蜂毒液肌肽增强细胞机制
5. Robot-driven Epidural Spinal Cord Stimulation Compared with Conventional Stimulation in Adult Spinalized Rats. [D] . Hsieh, Fu-Han. 2011

机译：机器人驱动硬膜外脊髓刺激与成年脊髓大鼠的常规刺激相比。
6. Plasticity in expression of the glutamate transporters GLT-1 and GLAST in spinal dorsal horn glial cells following partial sciatic nerve ligation [O] . Wen-Jun Xin, Han-Rong Weng, Patrick M Dougherty 2009

机译：坐骨神经部分结扎后脊髓背角神经胶质细胞谷氨酸转运蛋白GLT-1和GLAST表达的可塑性
7. Plasticity in Expression of the Glutamate Transporters GLT-1 and GLAST in Spinal Dorsal Horn Glial Cells following Partial Sciatic Nerve Ligation [O] . Wen-Jun Xin, Han-Rong Weng, Patrick M Dougherty 2009

机译：部分坐骨神经结扎后脊髓背角胶质细胞谷氨酸转运蛋白GLT-1和GLAST表达的可塑性

Effect of electrical stimulation of sciatic nerve on synaptic plasticity of spinal dorsal horn and spinal c-fos expression in neonatal, juvenile and adult rats.

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