Functionalized Fe _3O _4 nanoparticles for detecting zinc ions in living cells and their cytotoxicity

Kang G.; Son H.; Lim J.M.; Kweon H.-S.; Lee I.S.; Kang D.; Jung J.H.

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Functionalized Fe _3O _4 nanoparticles for detecting zinc ions in living cells and their cytotoxicity

机译：功能化的Fe _3O _4纳米颗粒用于检测活细胞中的锌离子及其细胞毒性

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The zinc tank: A new fluoro-chromogenic chemosensor based on BODIPY-functionalized Fe _3O _4 nanoparticles (1) has been prepared. Chemoprobe 1 exhibits high selectivity for Zn ~(2+) over other competing metal ions tested. Moreover, confocal microscopy experiments established that 1 can be used for detecting Zn ~(2+) levels in living cells (see figure).

机译：锌罐：基于BODIPY功能化的Fe _3O _4纳米粒子（1）的新型荧光显色化学传感器已经制备。化学探针1对Zn〜（2+）具有比其他测试的竞争性金属离子更高的选择性。此外，共聚焦显微镜实验确定1可用于检测活细胞中的Zn〜（2+）水平（见图）。

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《Chemistry: A European journal》 |2012年第19期|共5页
作者
Kang G.; Son H.; Lim J.M.; Kweon H.-S.; Lee I.S.; Kang D.; Jung J.H.;
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正文语种 eng
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关键词
biosensors; chromophores; fluorophores; nanoparticles; zinc;

机译：生物传感器;发色团;荧光团;纳米粒子;锌;

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专利

1. Functionalized Fe _3O _4 nanoparticles for detecting zinc ions in living cells and their cytotoxicity [J] . Kang G., Son H., Lim J.M., Chemistry: A European journal . 2012,第19期

机译：功能化的Fe _3O _4纳米颗粒用于检测活细胞中的锌离子及其细胞毒性
2. A Highly Sensitive and Selective Turn-On Fluorogenic and Chromogenic Sensor Based on BODIPY-Functionalized Magnetic Nanoparticles for Detecting Lead in Living Cells [J] . Hyunjong Son, Hye Young Lee, Jung Mi Lim, Chemistry - A European Journal . 2010,第38期

机译：基于BODIPY功能化磁性纳米粒子的高灵敏选择性开启式荧光和生色传感器，用于检测活细胞中的铅
3. Cytotoxicity evaluation of magnetite (Fe _3O _4) nanoparticles in mouse embryonic stem cells [J] . Shundo C., Zhang H., Nakanishi T., Colloids and Surfaces, B. Biointerfaces . 2012,第Null期

机译：磁铁矿（Fe _3O _4）纳米粒子在小鼠胚胎干细胞中的细胞毒性评估
4. Cytotoxic studies of PEG functionalized ZnO Nanoparticles on MCF-7 cancer cells [C] . Carla Rodriguez Martinez, Prachi Joshi, Jose L.Vera, NSTI nanotechnology conference and expo;Nanotech conference expo;NSTI-Nanotech 2011;TechConnect world annual conference expo . 2011

机译：PEG功能化ZnO纳米粒子对MCF-7癌细胞的细胞毒性研究
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机译：微流体芯片的设计研究硅氧纳米线检测到的抗原驱动电压电位差异的潜在使用，其用抗体官能化树枝状大分子进一步涂覆的金纳米颗粒进行抗体 - 官能化的树枝状大分子进行后诊断
6. Zinc oxide nanoparticles modulate the gene expression of ZnT1 and ZIP8 to manipulate zinc homeostasis and stress-induced cytotoxicity in human neuroblastoma SH-SY5Y cells [O] . Chien-Yuan Pan, Fang-Yu Lin, Lung-Sen Kao, 2020

机译：氧化锌纳米粒子调节ZnT1和Zip8的基因表达以操纵人神经母细胞瘤SH-SE5Y细胞中的锌稳态和胁迫诱导的细胞毒性
7. Palladium(II) Pincer Complexes of Functionalized Amides with SModified Cysteine and Homocysteine Residues: Cytotoxic Activity and Different Aspects of Their Biological Effect on Living Cells [O] . -1

机译：钯（II）磷酸盐络合物的官能化酰胺与令人生气的半胱氨酸和同型半胱氨酸残基：细胞毒性活性和它们对活细胞生物学作用的不同方面

Functionalized Fe _3O _4 nanoparticles for detecting zinc ions in living cells and their cytotoxicity

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