Transition-metal-free synthesis of aryl-substituted tert-butyl ynol ethers through addition/elimination substitution at an sp centre

Gray V.J.; Slater B.; Wilden J.D.

首页> 外文期刊>Chemistry: A European journal >Transition-metal-free synthesis of aryl-substituted tert-butyl ynol ethers through addition/elimination substitution at an sp centre

【24h】

Transition-metal-free synthesis of aryl-substituted tert-butyl ynol ethers through addition/elimination substitution at an sp centre

机译：通过在sp中心进行加成/消除取代反应实现无过渡金属合成芳基取代的叔丁基ynol醚

获取原文

获取原文并翻译 | 示例

掌桥外文数据库（机构版） >>

开具论文收录证明 >>

文献代查 >>

页面导航

摘要
著录项
相似文献
相关主题

摘要

Nucleophilic attack of an alkoxide on an alkynyl sulfonamide leads to displacement of the sulfonamide at the sp centre and isolation of the ynol ether in good yield in a single operation (see scheme). The mechanistic pathway has been probed by the use of coordinating additives, ~(13)C-labelling experiments and ab initio calculations, which indicated that an addition/elimination mechanism is in operation.

机译：醇盐对炔基磺酰胺的亲核攻击会导致磺酰胺在sp中心发生置换，并在一次操作中以高收率分离出炔诺醚（请参见方案）。通过使用配位添加剂，〜（13）C标记实验和从头算来探究机理途径，这表明添加/消除机理正在发挥作用。

著录项

来源
《Chemistry: A European journal》 |2012年第49期|共4页
作者
Gray V.J.; Slater B.; Wilden J.D.;
展开▼
作者单位

展开▼
收录信息
原文格式 PDF
正文语种 eng
中图分类
关键词
alkynes; elimination; sp substitution; sulfonamides; synthetic methods;

机译：炔烃;消除;sp取代;磺酰胺;合成方法;

相似文献

外文文献
中文文献
专利

1. Transition-metal-free synthesis of aryl-substituted tert-butyl ynol ethers through addition/elimination substitution at an sp centre [J] . Gray V.J., Slater B., Wilden J.D. Chemistry: A European journal . 2012,第49期

机译：通过在sp中心进行加成/消除取代反应实现无过渡金属合成芳基取代的叔丁基ynol醚
2. Transition-Metal-Free Synthesis of Ynol Ethers and Thioynol Ethers via Displacement at sp Centers: A Revised Mechanistic Pathway [J] . Vincent James Gray, James Cuthbertson, Jonathan D. Wilden The Journal of Organic Chemistry . 2014,第12期

机译：通过sp中心的位移实现无过渡金属合成的Ynol醚和硫醇醚的合成：一种修正的机理途径
3. Synthesis of alkyl-ynol-ethers by "anti-Michael addition" of metal alkoxides to β-substituted alkynylsulfones [J] . Marzo L., Parra A., Frías M., European journal of organic chemistry . 2013,第20期

机译：通过将金属醇盐“反迈克尔加成”到β-取代的炔基砜上合成烷基-炔醇醚
4. Methyl tert-butyl ether (MTBE) elimination by cometabolism: laboratory and biofilter pilot-scale results [C] . Adriana Hernandez, Miguel Magana, Beatriz Cardenas Air Waste Management Association's Annual conference Exhibition . 2001

机译：Cometabolism消除甲基叔丁基醚（MTBE）：实验室和生物过滤器试验结果
5. Biodegradation of methyl tert-butyl ether (MTBE) and its breakdown products by propane and iso-pentane grown Mycobacterium vaccae and Graphium sp.: Cometabolism, inhibition, kinetics and modeling. [D] . Martinez-Prado, Maria Adriana. 2002

机译：丙烷和异戊烷生长的牛分枝杆菌和Graphium sp。对甲基叔丁基醚（MTBE）及其分解产物的生物降解：代谢，抑制，动力学和建模。
6. Addition of Organochromium Reagents to Heteroaryl Aldehydes. Synthesis of Heteroaryl Substituted bis-Allyl Ethers and Homoallyl Ethers [O] . S. Servi, C. Topaloglu 2004

机译：在杂芳基醛中添加有机铬试剂。杂芳基取代的双烯丙基醚和均烯丙基醚的合成
7. An improved transition-metal-free synthesis of aryl alkynyl sulfides via substitution of a halide at an sp-centre [O] . Roomi Mohima Chowdhury, Jonathan D. Wilden 2015

机译：通过在SP中心取代卤化物通过卤化物改善芳基炔基硫化物的改进的过渡 - 金属合成

Transition-metal-free synthesis of aryl-substituted tert-butyl ynol ethers through addition/elimination substitution at an sp centre

摘要

著录项

相似文献

相关主题

期刊订阅