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首页> 外文期刊>Anticancer Research: International Journal of Cancer Research and Treatment >Primary Gastric Small Cell Carcinoma: A Series of Seven Cases
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Primary Gastric Small Cell Carcinoma: A Series of Seven Cases

机译：原发性胃小细胞癌：七例系列

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摘要

Aim: To present a series of seven cases of gastric. small cell carcinoma (GSCC) treated surgically and to illustrate the clinicopathological features and clinical course. Patients and Methods: Among 1,832 patients with gastric cancer who underwent gastric resection between 1997 and 2012, we reviewed the clinical records of 7 patients with histopathological diagnoses of GSCC. Results: No patients had preoperative confirmation of GSCC from endoscopic biopsy. Curative resection (RO) was achieved in 5 patients (71.4%). Two out of the 5 patients with curative resection survived more than four years. Two out of 3 patients who received weekly paclitaxel had progression-free survival of more than 10 months. The median survival time for the whole patient group was 14 months and the 3-year survival rate was 25.0%. Conclusion: Curative surgery with adjuvant chemotherapy may be essential to improve the prognosis of GSCC, and weekly paclitaxel chemotherapy may represent a promising chemotherapy for GSCC.
机译：目的：介绍一系列七例胃病。手术治疗的小细胞癌（GSCC），以说明其临床病理特征和临床过程。患者和方法：在1997年至2012年间接受胃切除术的1,832例胃癌患者中，我们回顾了7例经组织病理学诊断为GSCC的患者的临床记录。结果：没有患者术前经内镜活检证实为GSCC。 5例（71.4％）达到根治性切除（RO）。 5例根治性切除术中有2例生存超过四年。每周接受紫杉醇治疗的3名患者中，有2名的无进展生存期超过10个月。整个患者组的中位生存时间为14个月，三年生存率为25.0％。结论：辅助化疗治疗可能是改善GSCC预后的关键，每周紫杉醇化疗可能是GSCC的有希望的化疗方法。

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