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首页> 外文期刊>Contraception >Effects of the contraceptive vaginal ring, the contraceptive transdermal patch and combined oral contraceptives on markers of hemostasis.
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Effects of the contraceptive vaginal ring, the contraceptive transdermal patch and combined oral contraceptives on markers of hemostasis.

机译:阴道环避孕药,透皮避孕药和联合口服避孕药对止血指标的影响。

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摘要

Recently, Jensen et al. published a study in which they assessed the effect of switching from combined oral contraceptives to the combined) contraceptive vaginal ring or transdermal patch on markers of hemostasis that have been related to the risk of venous thrombosis. The authors conclude that switching from an oral contraceptive to the ring causes beneficial changes in these markers, while switching from an oral contraceptive to the patch leads to unfavorable changes in markers of thrombotic risk. In contrast with the results of Jensen et al., we observed a prothrombotic effect of both the ring and the patch compared to an oral contraceptive. The differences in outcomes between the studies might be explained by (1) difference in comparator oral contraceptive, (2) difference in laboratory methods and (3) methodological differences.
机译:最近,Jensen等人。发表了一项研究,他们评估了从联合口服避孕药改为联合避孕阴道环或透皮贴剂对止血标志物的影响,这些止血标志物与静脉血栓形成的风险有关。作者得出的结论是,从口服避孕药切换到戒指会导致这些标志物发生有益变化,而从口服避孕药切换到贴剂会导致血栓风险标志物发生不利变化。与Jensen等人的结果相反,与口服避孕药相比,我们观察到了环和贴剂的促血栓作用。两项研究之间的结果差异可以通过(1)比较口服避孕药的差异,(2)实验室方法的差异和(3)方法学的差异来解释。

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