首页> 外文期刊>Cortex: A Journal Devoted to the Study of the Nervous System and Behavior >The riddle of anosognosia: Does unawareness of hemiplegia involve a failure to update beliefs?
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The riddle of anosognosia: Does unawareness of hemiplegia involve a failure to update beliefs?

机译:失语症之谜:对偏瘫的不了解是否会导致观念更新失败?

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Anosognosia for hemiplegia (AHP) is defined as a lack of awareness for motor incapacity after a brain lesion. The causes of AHP still remain poorly understood. Many associations and dissociations with other deficits have been highlighted but no specific cognitive or neurological impairment has been identified as a unique causative factor. We hypothesized that a failure to update beliefs about current state might be a crucial component of AHP. Here, we report results from a new test that are compatible with this view. We examined anosognosic and nosognosic brain-damaged patients, as well as healthy controls, on a task where they had to guess a target word based on successive clues, with increasing informative content. After each clue, participants had to propose a word solution and rated their confidence. Compared to other participants, anosognosic patients were abnormally overconfident in their responses, even when information from the clues was insufficient. Furthermore, when presented with new clues incongruent with their previous response, they often stuck to their former "false" beliefs instead of modifying them. This impairment was unrelated to global deficits in reasoning or memory, and all patients eventually identified the correct solution of riddles after the last, fully informative, clue. These results suggest that a deficit in the generation and adjustment of beliefs may be a key factor contributing to the occurrence and persistence of anosognosia, when associated with concomitant losses in motor, proprioceptive, and/or attentional functions. Patients may remain unaware of their deficit partly because they cannot "update" their beliefs about current state.
机译:偏瘫(AHP)的厌食症定义为对脑损伤后缺乏运动能力丧失的认识。对AHP的原因仍然知之甚少。与其他缺陷的许多关联和分离已被强调,但没有特定的认知或神经功能障碍被鉴定为独特的病因。我们假设未能更新有关当前状态的信念可能是AHP的重要组成部分。在这里,我们报告了与该视图兼容的新测试的结果。我们检查了失语症患者和不知觉性大脑受损患者以及健康对照者的任务,即他们必须根据连续的线索猜测目标词,并提供更多的信息。在每个线索之后,参与者必须提出一个单词解决方案,并对自己的信心进行评估。与其他参与者相比,厌食症患者的反应异常过分自信,即使来自线索的信息不足也是如此。此外,当出现与他们先前反应不符的新线索时,他们通常会坚持以前的“错误”信念,而不是对其进行修改。这种损害与推理或记忆的整体缺陷无关,并且所有患者最终都在最后一个充分提供信息的线索之后确定了谜语的正确解决方案。这些结果表明,与运动,本体感受和/或注意功能的伴随丧失相关联时,信念的产生和调整不足可能是导致失语症发生和持续的关键因素。患者可能仍未意识到自己的不足,部分原因是他们无法“更新”对当前状态的看法。

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