Heterozygous Pitx2 Null Mice Accurately Recapitulate the Ocular Features of Axenfeld-Rieger Syndrome and Congenital Glaucoma

Chen Lisheng; Gage Philip J.

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Heterozygous Pitx2 Null Mice Accurately Recapitulate the Ocular Features of Axenfeld-Rieger Syndrome and Congenital Glaucoma

机译：杂合Pitx2空小鼠准确地概括了Axenfeld-Rieger综合征和先天性青光眼的眼部特征

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摘要

PURPOSE. The purpose of this analysis was to assess the utility of Pitx2(+/)-mice as a model for the ocular features of Axenfeld-Rieger Syndrome and for congenital glaucoma.

机译：目的。该分析的目的是评估Pitx2（+ /）-小鼠作为Axenfeld-Rieger综合征眼功能和先天性青光眼模型的效用。

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《Investigative ophthalmology & visual science》 |2016年第11期|共8页
作者
Chen Lisheng; Gage Philip J.;
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正文语种 eng
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Pitx2; homeodomain; mouse model;

机译：Pitx2;homeodomain;鼠标模型;

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专利

1. Heterozygous Pitx2 Null Mice Accurately Recapitulate the Ocular Features of Axenfeld-Rieger Syndrome and Congenital Glaucoma [J] . Lisheng Chen, Philip J. Gage Investigative ophthalmology & visual science . 2016,第11期

机译：杂合Pitx2空小鼠准确地概括了Axenfeld-Rieger综合征和先天性青光眼的眼部特征
2. Heterozygous Pitx2 Null Mice Accurately Recapitulate the Ocular Features of Axenfeld-Rieger Syndrome and Congenital Glaucoma [J] . Chen Lisheng, Gage Philip J. Investigative ophthalmology & visual science . 2016,第11期

机译：杂合Pitx2空小鼠准确地概括了Axenfeld-Rieger综合征和先天性青光眼的眼部特征
3. Heterozygous Pitx2 Null Mice Accurately Recapitulate the Ocular Features of Axenfeld-Rieger Syndrome and Congenital Glaucoma [J] . Chen Lisheng, Gage Philip J. Investigative ophthalmology & visual science . 2016,第11期

机译：杂合Pitx2空小鼠准确地概括了Axenfeld-Rieger综合征和先天性青光眼的眼部特征
4. The molecular mechanisms of PITX2 in tooth development and enamel defects in Axenfeld-Rieger Syndrome. [D] . Li, Xiao. 2013

机译：PITX2在Axenfeld-Rieger综合征的牙齿发育和釉质缺损中的分子机制。
5. Heterozygous Pitx2 Null Mice Accurately Recapitulate the Ocular Features of Axenfeld-Rieger Syndrome and Congenital Glaucoma [O] . Lisheng Chen, Philip J. Gage -1

机译：杂合Pitx2空小鼠准确地概括了Axenfeld-Rieger综合征和先天性青光眼的眼部特征
6. HeterozygousPitx2Null Mice Accurately Recapitulate the Ocular Features of Axenfeld-Rieger Syndrome and Congenital Glaucoma [O] . Lisheng Chen, Philip J. Gage 2016

机译：杂合子戊百合小鼠精确地重新延长Axenfeld-Rieger综合征和先天性青光眼的眼部特征
7. Disruption of NBS1 gene leads to early embryonic lethality in homozygous null mice and induces specific cancer in heterozygous mice [R] . 2002

机译：NBs1基因的破坏导致纯合无效小鼠的早期胚胎致死率并诱导杂合小鼠中的特定癌症

Heterozygous Pitx2 Null Mice Accurately Recapitulate the Ocular Features of Axenfeld-Rieger Syndrome and Congenital Glaucoma

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