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A Portable Microkeratome for Harvesting the Human Anterior Corneal Surface.

机译:用于收获人角膜前表面的便携式微型角膜刀。

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摘要

A portable, gas-driven turbine microkeratome device capable of harvesting the entire anterior corneal surface for lamellar transplantation on human donor globes was evaluated. The device consisted of a modified LASIK microkeratome with an enlarged suction ring, head, and blade. Vacuum was achieved by a simple hand pump. Lamellar keratectomy was performed on 5 fresh human donor globes. Lenticule dimensions were measured on days 0, 3, 6, and 9 after storage in preservation media at 4 degrees C. On day 0, the obtained lenticules were 13.9 +/- 0.9 mm and 13.5 +/- 0.4 mm, vertical and horizontal diameters, respectively. The average central lenticule thickness was 152.2 +/- 52 microm. Each lenticule was uniform in thickness over 5 measurement points (P = 0.74). Repeat measurements of corneal thickness over the 9 days showed no statistically significant difference (P = 0.51). On day 9 lenticules were 14.6 +/- 0.3 mm and 14.6 +/- 0.4 mm, vertical and horizontal diameters, respectively. When day 0 was compared to day 9, vertical diameter also showed no statistically significant difference (P = 0.16), whereas horizontal diameter was significantly different (P < 0.001). This device proves to be an economical alternative to electric-powered systems for the harvest of transplantable corneal sections.
机译:对便携式气体驱动涡轮微型角膜刀装置进行了评估,该装置能够收获整个角膜前表面,用于在人供体上进行层状移植。该设备由改良的LASIK微型角膜刀组成,该微型角膜刀具有增大的吸力环,头部和刀片。通过简单的手动泵即可达到真空。层状角膜切除术是在5个新鲜的人类供体球上进行的。在4℃下保存在保存介质中后的第0、3、6和9天测量微透镜尺寸。在第0天,获得的微透镜为13.9 +/- 0.9mm和13.5 +/- 0.4mm,垂直和水平直径, 分别。平均中央小透镜厚度为152.2 +/- 52微米。每个微透镜在5个测量点上的厚度均一(P = 0.74)。在9天中重复测量角膜厚度未显示出统计学上的显着差异(P = 0.51)。在第9天,小透镜的垂直直径和水平直径分别为14.6 +/- 0.3mm和14.6 +/- 0.4mm。当将第0天与第9天进行比较时,垂直直径也没有显示出统计学上的显着差异(P = 0.16),而水平直径则存在显着差异(P <0.001)。该设备被证明是用于收获可移植角膜切片的电动系统的经济替代品。

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