• 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Cornea >Clinical profile and risk factors for keratoplasty and development of hydrops in north Indian patients with keratoconus.
【24h】

Clinical profile and risk factors for keratoplasty and development of hydrops in north Indian patients with keratoconus.

机译：印度北部圆锥角膜患者的角膜移植和积水发展的临床资料和危险因素。

获取原文
获取原文并翻译 | 示例
       
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

PURPOSE: To review the profile of Indian patients with keratoconus and evaluate risk factors for keratoplasty and development of hydrops. METHODS: In this prospective observational study, 120 consecutive patients with bilateral or unilateral keratoconus presenting to the cornea services of a large, tertiary care ophthalmic center were evaluated. A detailed history including information about the age at onset of symptoms, nature of ocular complaints, and so on was taken. Investigations included visual acuity, slit-lamp examination, keratometry, pachymetry, and videokeratography. RESULTS: There were 76 males and 44 females (mean age at presentation was 20.07 +/- 6.4 years). Five percent families revealed a positive family history. Earlier age at onset (P = 0.002) and eye rubbing (P = 0.02) were found significantly associated with increased risk for surgery. Eyes undergoing surgery had steeper corneas, lower best-corrected visual acuity, corneal scarring, and vernal keratoconjunctivitis were significant risk factors (P values: 0.001, 0.0001, and 0.04, respectively). Hydrops represents a significant independent risk factor for surgery (P = 0.0001). Patients with younger age at onset (P value 0.01), history of eye rubbing (P value 0.02), and atopy (P value 0.01) had higher risk for developing corneal hydrops. CONCLUSION: This knowledge of risk factors should enable clinicians and patients to make more informed decisions regarding the management of keratoconus.
机译：目的：审查印度圆锥角膜患者的概况，并评估角膜移植术和积液发展的危险因素。方法：在这项前瞻性观察研究中，对120名连续的双侧或单侧圆锥角膜患者在大型三级眼科中心的角膜服务中进行了评估。详细的历史记录包括有关症状发作的年龄，眼部不适的性质等信息。调查包括视力，裂隙灯检查，角膜曲率法，测厚法和视频角膜描记法。结果：男性76例，女性44例（报告时的平均年龄为20.07 +/- 6.4岁）。 5％的家庭显示出积极的家族史。发现发病年龄较早（P = 0.002）和揉眼（P = 0.02）与手术风险增加显着相关。进行手术的眼睛角膜较陡，矫正视力较低，角膜瘢痕形成和春季角膜结膜炎是重要的危险因素（P值分别为0.001、0.0001和0.04）。积液代表手术的重要独立危险因素（P = 0.0001）。发病年龄较小（P值0.01），有揉眼病史（P值0.02）和特应性过敏（P值0.01）的患者发生角膜积液的风险较高。结论：对危险因素的了解应使临床医生和患者能够就圆锥角膜的治疗做出更明智的决定。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号