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首页> 外文期刊>Controlled clinical trials >Leading the Way in Exercise and Diet (Project LEAD): intervening to improve function among older breast and prostate cancer survivors.
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Leading the Way in Exercise and Diet (Project LEAD): intervening to improve function among older breast and prostate cancer survivors.

机译:领导运动和饮食方式(铅项目):干预以改善老年乳腺癌和前列腺癌幸存者的功能。

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摘要

The U.S. population is aging, bringing with it an increased prevalence of chronic disease and concomitant declines in physical function. The risk of developing cancer increases significantly with age, and functional decline is much more likely once a cancer diagnosis is rendered. Thus, functional status in later life is a key concern, one that is heightened among elders who have been diagnosed with cancer. To date, however, there have been few trials that have exclusively addressed issues related to cancer survivorship among older cancer patients, and to our knowledge, none has focused on preserving or enhancing physical functioning. This paper describes the study design and methodological considerations of a randomized controlled trial to determine if a personally tailored workbook and telephone counseling program can positively affect physical activity and dietary behaviors and ultimately the physical functioning of up to 420 older men and women newly diagnosed with breast or prostate cancer. This trial is unique because the cancer diagnosis is used not only as a marker of risk for functional decline, but also as a "teachable moment" - an opportune time when elders may be more receptive to making beneficial lifestyle changes. Undoubtedly, as cure rates for cancer increase and intersect with ever-growing numbers of elderly, there will be numerous opportunities to provide and test interventions within this vulnerable population and to target functional status as a primary outcome. In reporting our methods, we hope to give others "a leg up," so that they can hurdle with greater ease the barriers we experienced, and thus advance the field more rapidly.
机译:美国人口正在老龄化,随之而来的是慢性病的患病率上升以及身体机能的下降。随着年龄的增长,患癌症的风险显着增加,一旦做出癌症诊断,功能下降的可能性就更大。因此,晚年的功能状态是一个关键问题,这一点在被诊断出患有癌症的老年人中尤为突出。然而,迄今为止,很少有试验专门研究与老年癌症患者的癌症生存相关的问题,并且据我们所知,没有一项试验着重于保持或增强身体机能。本文描述了一项随机对照试验的研究设计和方法学考虑因素,以确定个人量身定制的工作簿和电话咨询计划是否可以积极影响体育活动和饮食行为,并最终影响多达420名刚被诊断出患有乳腺疾病的男性和女性或前列腺癌。该试验之所以独特,是因为癌症诊断不仅被用作功能下降风险的标志,而且还被用作“可教的时刻”,这是老年人可能更乐于接受有益的生活方式改变的适当时机。毫无疑问,随着癌症治愈率的提高和与越来越多的老年人相交,将有大量机会在这一脆弱人群中提供和测试干预措施,并将功能状态作为主要目标。在报告我们的方法时,我们希望让其他人“站起来”,以便他们可以更轻松地克服我们遇到的障碍,从而更快地推进该领域。

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