An eco-friendly protocol for synthesis of thiourea derivatives: 1-benzoyl-3-benzylguanidine and 1-benzoyl-3-benzyl-O-ethylisourea. A possible non-purely thermal microwave assisted reaction

Marquez H; Loupy A; Calderon O; Perez ER

首页> 外文期刊>Tetrahedron >An eco-friendly protocol for synthesis of thiourea derivatives: 1-benzoyl-3-benzylguanidine and 1-benzoyl-3-benzyl-O-ethylisourea. A possible non-purely thermal microwave assisted reaction

【24h】

An eco-friendly protocol for synthesis of thiourea derivatives: 1-benzoyl-3-benzylguanidine and 1-benzoyl-3-benzyl-O-ethylisourea. A possible non-purely thermal microwave assisted reaction

机译：合成硫脲衍生物的生态友好方案：1-苯甲酰基-3-苄基胍和1-苯甲酰基-3-苄基-O-乙基异脲。可能的非纯热微波辅助反应

获取原文

获取原文并翻译 | 示例

掌桥外文数据库（机构版） >>

开具论文收录证明 >>

文献代查 >>

页面导航

摘要
著录项
相似文献
相关主题

摘要

1-Benzoyl-3-benzylguanidine and 1-benzoyl-3-benzyl-O-ethylisourea were synthesized in good yields (68 and 76%, respectively) from 1-benzoyl-3-benzylthiourea and benzoyl-ethylthiocarbamate in dry media conditions using KF-Al2O3 under microwave irradiation. Strong nucleophilic amines promoted the sulfur elimination by attack on the thiocarbonyl group in both thiourea and thiocarbamates to afford guanidines and isourea, respectively. Transesterification products were obtained from p-TsOH catalyzed reaction of thiocarbamate with alcohols under MW-solvent-free conditions. Very important non-purely thermal MW specific effects were evidenced and attributed to stabilization by coulombic interactions between materials and waves. (c) 2005 Elsevier Ltd. All rights reserved.

机译：使用KF在干燥介质条件下从1-苯甲酰基-3-苄基硫脲和苯甲酰基-乙基硫代氨基甲酸酯以良好的收率（分别为68％和76％）合成了1-苯甲酰基-3-苄基胍和1-苯甲酰基-3-苄基-O-乙基异脲-Al2O3在微波辐射下。强亲核胺通过攻击硫脲和硫代氨基甲酸酯中的硫代羰基而促进了硫的消除，从而分别提供了胍和异脲。在无MW溶剂的条件下，由p-TsOH催化的硫代氨基甲酸酯与醇的反应获得酯交换产物。证明了非常重要的非纯热MW特有效应，并归因于物质与波浪之间的库仑相互作用而稳定。（c）2005 Elsevier Ltd.保留所有权利。

著录项

来源
《Tetrahedron》 |2006年第11期|共6页
作者
Marquez H; Loupy A; Calderon O; Perez ER;
展开▼
作者单位

展开▼
收录信息
原文格式 PDF
正文语种 eng
中图分类
关键词
1-benzoyl-3-benzylguanidine; 1-benzoyl-3-benzyl-O-ethylisourea; thiocarbamates; microwave irradiation; solvent-free conditions; SOLID-PHASE SYNTHESIS; HGCL2-PROMOTED GUANYLATION REACTION; ONE-POT SYNTHESIS; ORGANIC-SYNTHESIS; CARBOXYLIC-ACIDS; O-ALKYLISOUREAS; DRY-MEDIA; GUANIDINES; IRRADIATION; ALKYLATION;

机译：1-苯甲酰基-3-苄基胍;1-苯甲酰基-3-苄基-O-乙基异脲;硫代氨基甲酸酯;微波辐射;无溶剂条件;固相合成;HGCL2-促进的胍基反应;一锅合成;有机合成;羧酸;邻烷基异脲;干介质;胍类;辐照;烷基化;

相似文献

外文文献
中文文献
专利

1. An eco-friendly protocol for synthesis of thiourea derivatives: 1-benzoyl-3-benzylguanidine and 1-benzoyl-3-benzyl-O-ethylisourea. A possible non-purely thermal microwave assisted reaction [J] . Marquez H, Loupy A, Calderon O, Tetrahedron . 2006,第11期

机译：合成硫脲衍生物的生态友好方案：1-苯甲酰基-3-苄基胍和1-苯甲酰基-3-苄基-O-乙基异脲。可能的非纯热微波辅助反应
2. Microwave-Assisted K-10 Montmorillonite Clay-Mediated Knoevenagel Hetero-Diels-Alder Reactions: A Novel Protocol for the Synthesis of Polycyclic Pyrano[2,3,4-kl]xanthene Derivatives [J] . Ramesh E, Raghunathan R Synthetic Communications . 2009,第4a6期

机译：微波辅助的K-10蒙脱土粘土介导的Knoevenagel杂Diels-Alder反应：合成多环吡喃并[2,3,4-kl]氧杂蒽衍生物的新协议
3. Microwave assisted multicomponent reaction: An environmentally benign protocol for the synthesis of substituted imidazo[2,1-b]thiazole-2-carbohydrazide derivatives under solvent free condition [J] . Shuddhodan Narhari Kadam, Ajay Niwruttirao Ambhore, Milind Vithalrao Gaikwad European Journal of Chemistry . 2016,第4期

机译：微波辅助多组分反应：无溶剂条件下合成咪唑并[2,1-b]噻唑-2-碳酰肼衍生物的环境友好方案
4. Synthesis of Iri2Se3 and Cu_(2-x)Se Micro-and Nanoparticles with Microwave-Assisted Solvothermal and Aqueous Redox Reactions for the Preparation and Stabilization of Printable Precursors for a CuInSe2 Solar Cell Absorber Layer [C] . Matthias Schuster, Monica Distaso, Stefan A. Mockel EMRS Meeting on Advanced Inorganic Materials and Structures for Photovoltaics . 2016

机译：用微波辅助溶解的溶剂热和纳米颗粒合成IRI2Se3和Cu_（2-X）Se微型和纳米颗粒，用于制备和稳定用于CuinSe2太阳能电池吸收层的可印刷前体
5. I. Enantioselective total synthesis of quinine and quinidine. II. Thiourea-catalyzed enantioselective C-C bond-forming reactions. a. Catalytic asymmetric N-acyliminium ion cyclizations. b. Catalytic asymmetric aza-Baylis-Hillman reactions [D] . Raheem, Izzat Tiedje 2008

机译：I.奎宁和奎尼丁的对映选择性全合成。二。硫脲催化的对映选择性C-C键形成反应。一个。催化不对称N-酰亚胺离子环化。 b。催化不对称氮杂-Baylis-Hillman反应
6. Microwave-assisted Hantzsch thiazole synthesis of N-phenyl-4-(6-phenylimidazo21-bthiazol-5-yl)thiazol-2-amines from the reaction of 2-chloro-1-(6-phenylimidazo21-bthiazol-5-yl)ethanones and thioureas [O] . Sukanta Kamila, Kimberly Mendoza, Edward R. Biehl -1

机译：微波辅助Hantzsch噻唑合成N-苯基-4-（6-苯基咪唑21-B噻唑-5-基）从2-氯-1-（6-苯基咪唑的反应中的噻唑-2-胺 21-b噻唑-5-基）乙醇和硫脲
7. Microwave assisted multicomponent reaction: An environmentally benign protocol for the synthesis of substituted imidazo2,1-bthiazole-2-carbohydrazide derivatives under solvent free condition [O] . Shuddhodan Narhari Kadam, Ajay Niwruttirao Ambhore, Milind Vithalrao Gaikwad, 2016

机译：微波辅助多组分反应：在无溶剂条件下，用于合成取代的咪唑的环境良性方案2,1-B噻唑-2-碳水化合物衍生物

An eco-friendly protocol for synthesis of thiourea derivatives: 1-benzoyl-3-benzylguanidine and 1-benzoyl-3-benzyl-O-ethylisourea. A possible non-purely thermal microwave assisted reaction

摘要

著录项

相似文献

相关主题

期刊订阅