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Assessing vaccination coverage in infants, survey studies versus the Flemish immunisation register: Achieving the best of both worlds

机译：评估婴儿的疫苗接种覆盖率，调查研究与佛兰德免疫登记册的比较：做到两全其美

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Infant immunisation coverage in Flanders, Belgium, is monitored through repeated coverage surveys. With the increased use of Vaccinnet, the web-based ordering system for vaccines in Flanders set up in 2004 and linked to an immunisation register, this database could become an alternative to quickly estimate vaccination coverage. To evaluate its current accuracy, coverage estimates generated from Vaccinnet alone were compared with estimates from the most recent survey (2012) that combined interview data with data from Vaccinnet and medical files. Coverage rates from registrations in Vaccinnet were systematically lower than the corresponding estimates obtained through the survey (mean difference 7.7%). This difference increased by dose number for vaccines that require multiple doses. Differences in administration date between the two sources were observed for 3.8-8.2% of registered doses. Underparticipation in Vaccinnet thus significantly impacts on the register-based immunisation coverage estimates, amplified by underregistration of administered doses among vaccinators using Vaccinnet. Therefore, survey studies, despite being labour-intensive and expensive, currently provide more complete and reliable results than register-based estimates alone in Flanders. However, further improvement of Vaccinnet's completeness will likely allow more accurate estimates in the nearby future
机译：比利时法兰德斯的婴儿免疫接种覆盖率通过重复覆盖率调查进行监控。随着越来越多的Vaccinnet的使用，该网站于2004年在法兰德斯建立了基于网络的疫苗订购系统，并与免疫登记系统链接，该数据库可以成为快速估算疫苗接种覆盖率的替代方法。为了评估其当前准确性，仅将Vaccinnet产生的覆盖率估计值与最近一次调查（2012年）的估计值进行了比较，该调查将采访数据与Vaccinnet和医疗文件中的数据相结合。 Vaccinnet中注册的覆盖率总体上低于通过调查获得的相应估计值（平均差异为7.7％）。对于需要多次剂量的疫苗，这种差异增加了剂量数量。对于注册剂量的3.8-8.2％，观察到两种来源之间的给药日期差异。因此，参加疫苗接种网络的人数不足会严重影响基于登记册的免疫接种覆盖率估计值，而使用疫苗接种疫苗的接种者之间的疫苗剂量注册不足会加剧这种情况。因此，尽管在法兰德斯，调查研究尽管劳动强度大且昂贵，但目前提供的结果比仅基于登记册的估计结果更为完整和可靠。但是，Vaccinnet完整性的进一步改善可能会在不久的将来使估算更加准确

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