A combinatorial approach in designing hydrophilic surfaces for solid-phase peptide synthesis

Ercole F.; FitzGerald M.; Perera S.; Ede N.; Riley P.; Campbell R.

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A combinatorial approach in designing hydrophilic surfaces for solid-phase peptide synthesis

机译：设计亲水表面用于固相肽合成的组合方法

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A hydrophilic surface suitable for solid-state peptide synthesis was developed on a solid support called a lantern. The split-and-mix combinatorial technique was used to prepare about 500 surfaces in a very short time. Surfaces were analyzed according to values for gel formation, percentage weight grafted, grafted copolymer composition, and number of functional groups per lantern. These values were correlated to the purity of a peptide synthesized on these surfaces. (C) 2003 Wiley Periodicals, Inc. [References: 14]

机译：在称为灯笼的固体载体上显影了适合固态肽合成的亲水性表面。分离混合组合技术用于在很短的时间内制备约500个表面。根据凝胶形成，接枝的重量百分数，接枝的共聚物组成的百分比和每个灯的官能团数的值分析表面。这些值与在这些表面上合成的肽的纯度相关。（C）2003 Wiley Periodicals，Inc. [参考：14]

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《Journal of Applied Polymer Science》 |2003年第12期|共8页
作者
Ercole F.; FitzGerald M.; Perera S.; Ede N.; Riley P.; Campbell R.;
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正文语种 eng
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关键词
Pepticles; Synthesis; Surfaces; Supports; Grafted supports;

机译：消化剂;合成;表面;支持物;嫁接的支持物;

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A combinatorial approach in designing hydrophilic surfaces for solid-phase peptide synthesis

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