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首页> 外文期刊>Journal of Applied Polymer Science >Properties of polyacrylamide-based hydrogels prepared by electron beam irradiation for possible use as bioactive controlled delivery matrices
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Properties of polyacrylamide-based hydrogels prepared by electron beam irradiation for possible use as bioactive controlled delivery matrices

机译：通过电子束辐照制备的聚丙烯酰胺基水凝胶的性质可用作生物活性控制传递基质

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摘要

Polyacrylamide/poly(ethylene oxide) (PAAm/ PEO) crosslinked hydrogels were designed for controlled delivery of an herbicide, Atrazine, which is used in the agricultural field. Atrazine was incorporated into a PAAm/PEO matrix during an electron beam irradiation process. The Atrazine release rate from matrices prepared under different conditions was studied to determine which factors have the most affect and control over the PAAm/PEO matrix release property. The copolymer blend composition, copolymer gel content, and irradiation dose greatly affected the Atrazine release rate. In addition, its release rate was influenced by the pH and temperature of the matrix-surrounding medium. The Atrazine release rate decreased as the pH increased, but it increased as the temperature increased. The properties of the prepared crosslinked hydrogels may make them acceptable for practical use as bioactive controlled release matrices. (c) 2005 Wiley Periodicals, Inc.
机译：聚丙烯酰胺/聚环氧乙烷（PAAm / PEO）交联水凝胶设计用于可控地递送农业领域使用的除草剂阿特拉津。在电子束辐照过程中将去津掺入PAAm / PEO基质中。研究了在不同条件下制备的基质中r去津的释放速率，以确定哪些因素对PAAm / PEO基质的释放性能有最大的影响和控制。共聚物共混物的组成，共聚物凝胶含量和辐照剂量极大地影响了r去津的释放速率。另外，其释放速率受基质周围介质的pH和温度影响。阿特拉津的释放速率随pH的升高而降低，但随着温度的升高而升高。所制备的交联水凝胶的性质可使它们作为生物活性控释基质在实际应用中是可接受的。 （c）2005年Wiley Periodicals，Inc.

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