...
  • 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Journal of chromatography, A: Including electrophoresis and other separation methods >Analytical methods for the determination of bisphenol A in food
【24h】

Analytical methods for the determination of bisphenol A in food

机译：食品中双酚A的测定方法

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

Food constitutes the primary route for human exposure to bisphenol A (BPA), one of the highest volume chemicals produced worldwide. The estrogenic properties of BPA, its wide dispersive use and the recent extensive literature describing low-dose BPA effects in animals, have raised concerns about its possible adverse effects on human health. A reliable health risk assessment of BPA relies basically on its unambiguous identification and accurate quantification in food, and the aim of the present review is to give an overview of the analytical methods reported so far for the determination of BPA in these matrices. Emphasis is placed on the main strategies developed for sample treatment, which usually consists of several laborious and time-consuming steps in order to achieve the required sensitivity and selectivity. Separation, identification and quantitation of BPA is today reliably made with mass spectrometric methods, namely liquid chromatography-mass spectrometry (LC-MS) and gas chromatography-mass spectrometry (GC-MS), and thus main attention is devoted to these techniques, but other methods using LC coupled to fluorescence or electrochemical detection, as well as immunochemical methods are also covered. Recent and expected future developments are discussed. (C) 2008 Elsevier B.V. All rights reserved.
机译：食品是人类接触双酚A（BPA）的主要途径，双酚A是世界上生产量最大的化学品之一。 BPA的雌激素特性，其广泛的分散用途以及描述动物中低剂量BPA效应的最新文献表明，人们对BPA可能对人体健康产生不利影响感到担忧。对双酚A进行可靠的健康风险评估基本上取决于对食品中双酚A的明确鉴定和准确定量，本综述的目的是概述迄今为止报道的用于测定这些基质中双酚A的分析方法。重点放在为样品处理开发的主要策略上，该策略通常包括数个费力且费时的步骤，以实现所需的灵敏度和选择性。如今，BPA的分离，鉴定和定量可通过质谱方法可靠地完成，即液相色谱-质谱（LC-MS）和气相色谱-质谱（GC-MS），因此，主要关注这些技术，但是还涵盖了使用LC耦合荧光或电化学检测的其他方法以及免疫化学方法。讨论了近期和预期的未来发展。 （C）2008 Elsevier B.V.保留所有权利。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号