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首页> 外文期刊>Environmental Science and Pollution Research >Maternal fine particulate matter (PM2.5) exposure and adverse birth outcomes: an updated systematic review based on cohort studies
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Maternal fine particulate matter (PM2.5) exposure and adverse birth outcomes: an updated systematic review based on cohort studies

机译：母体细颗粒物质（PM2.5）暴露和不良出生结果：基于群组研究的更新系统审查

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Exposure to ambient air pollutants during pregnancy may be associated with numerous side health effects and adverse birth outcomes. Growing numbers of studies have explored a possible linkage between prenatal exposure to PM2.5 (particulate matter with aerodynamic diameter 2.5m) and impacts on fetal development. We aimed to conduct a systematic review based on published cohort studies to summarize evidence regarding the association between maternal PM2.5 exposure and birth outcomes, including birth weight, low birth weight (LBW), preterm birth (PTB), and small for gestational age (SGA). Eligible studies meeting the following criterion were selected: PM2.5 exposure during pregnancy and live birth singletons, certain presentation of sample sizes, and quantitative evaluation of the associations between exposure and outcomes. Among the 42 selected studies, 23 evaluated the impact of prenatal PM2.5 exposure on birth weight of infants while 12 of them provided a significantly negative association for exposure and birth weight. Twenty-one studies aimed to identify the possible relationship between maternal exposure and LBW and 8 studies proved significant associations. Among 18 studies that explored the correlation between prenatal exposure and PTB, 9 reached a consistent conclusion that gestational exposure would add to the risk of PTB. Nine studies assessed the impact of PM2.5 on SGA and 5 of them demonstrated a significant effect. So far, linkages between maternal PM2.5 exposure during varied gestational stages and multiple adverse birth outcomes have been observed in many studies. A summary of them will be meaningful for further research on maternal exposure and adverse birth outcomes.
机译：在妊娠期间暴露于环境空气污染物可能与许多副作用和不良出生结果相关。越来越多的研究已经探讨了产前暴露于PM2.5（具有空气动力学直径2.5米的颗粒物质）之间可能的联系，以及对胎儿发育的影响。我们旨在根据已发表的队列研究进行系统审查，总结有关母体PM2.5接触和出生结果之间的关联的证据，包括出生体重，低出生体重（LBW），早产（PTB），以及胎龄的小（SGA）。符合条件的研究符合以下标准的选择：PM2.5在怀孕期间暴露和活产出的单身，某些样本展示，以及暴露和结果之间的关联的定量评估。在42项选定的研究中，23评估产前PM2.5暴露对婴儿出生体重的影响，而其中12项为暴露和出生体重提供了显着的负关联。二十一项研究旨在确定母体暴露和LBW之间的可能关系，8研究证明了重要的协会。在18项研究中，探索产前暴露和PTB之间的相关性，9达到了一致的结论，即妊娠期暴露会增加PTB的风险。九项研究评估了PM2.5对SGA的影响，其中5种显示出显着效果。到目前为止，在许多研究中观察到母体PM2.5在各种妊娠期和多个不利出生结果期间接触的联系。他们的摘要将对母体暴露和不良出生结果进行进一步研究。

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