...
首页> 外文期刊>Life sciences >Growing knowledge of using embryonic stem cells as a novel tool in developmental risk assessment of environmental toxicants
【24h】

Growing knowledge of using embryonic stem cells as a novel tool in developmental risk assessment of environmental toxicants

机译:越来越多地了解使用胚胎干细胞作为环境毒物发育风险评估的新工具

获取原文
获取原文并翻译 | 示例
           

摘要

Developmental toxicology is an important area of novel toxicology. In recent years, there have been big concerns toward the increasing exposure to pharmaceutical agents, food additives, pesticides, occupational toxicants, and environmental pollutants, as well as their possible association with all aspects of male or female-mediated transient or permanent defects in progeny. Therefore, it is of great importance to look for new predictive models to evaluate environmental toxicants before they can harm the human health and embryo development. In this regard, new cell-based in vitro screening models have been developed and validated in predictive toxicology to minimize assay costs and animal usage.
机译:发育毒理学是新型毒理学的重要领域。 近年来,对药剂,食品添加剂,农药,职业毒物和环境污染物的不断增加,以及与雄性或女性介导的瞬态或永久性缺陷的所有方面的接触,促进了对药剂,食品添加剂,农药,职业毒物和环境污染物的影响。 。 因此,寻找新的预测模型,在危害人体健康和胚胎发育之前,寻找评估环境毒物的新预测模型非常重要。 在这方面,已经在预测性毒理学中开发并验证了新的基于细胞的体外筛选模型,以最大限度地减少测定成本和动物使用量。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱:kefu@zhangqiaokeyan.com

京公网安备:11010802029741号 ICP备案号:京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有
  • 客服微信

  • 服务号