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Qualitative and quantitative differences between common control banding tools for nanomaterials in workplaces

机译:工作场所纳米材料共同控制绷带工具之间的定性和定量差异

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摘要

A number of control banding (CB) tools have been developed specifically for managing the risk of exposure to engineered nanomaterials. However, data on the methodological differences between common CB tools for nanomaterials in workplaces are rare. A comparative study with different CB tools, such as Nanosafer, Stoffenmanager-Nano, Nanotool, Precautionary Matrix, ECguidance, IVAM Guidance, ISO, and ANSES, was performed to investigate their qualitative and quantitative differences in real exposure scenarios. These tools were developed for different purposes, with different application domains, methodological principles, and criteria. Multi-criteria analysis showed that there was a diverse distribution of these eight CB tools across different evaluation indicators. The total evaluation scores for Nanotool, Stoffenmanager-Nano, and Nanosafer were higher than the other tools. Quantitative comparisons demonstrated that ANSES, ECguidance, and IVAM Guidance tools were better in terms of information availability. Nanotool, Stoffenmanager-Nano, and ECguidance were better in terms of the sensitivity of outputs to changes in exposure parameters. The Nanotool, ANSES, and ECguidance tools were better in terms of accuracy of hazard outcomes evaluated with toxicological data. The Stoffenmanager-Nano, Nanotool, and Nanosafer tools' exposure scores for seven scenarios had a good correlation with measurement data. The Nanotool and Stoffenmanager-Nano tools had much higher comprehensive advantages based on quantitative and qualitative assessment. More comparative studies evaluating different tools are required, using more types of nanomaterials in real exposure scenarios.
机译:已经开发了许多控制带(CB)工具,用于管理暴露于工程纳米材料的风险。然而,关于工作场所中纳米材料的普通CB工具之间的方法论差异的数据是罕见的。进行了不同CB工具的比较研究,例如纳米辊,斯托夫•管理员 - 纳米,纳米工具,预防矩阵,eVGGE,IVAM指导,ISO和ANS,以研究实际曝光情景的定性和定量差异。这些工具是为不同目的而开发的,具有不同的应用领域,方法原则和标准。多标准分析表明,在不同的评估指标中,这8个CB工具的各种分布。纳米池,StoffenManager-nano和纳米孔的总评估分数高于其他工具。定量比较表明ANSES,EcGuidance和Ivam指导工具在信息可用性方面更好。基于输出对曝光参数变化的敏感性,Nanotool,StoffenManager-Nano和eVGoIdance更好。在毒理学数据评估的危害结果的准确性方面,纳米工具,ANSE和eVGEIDANCE工具更好。七种情景的斯托夫•管理器-Nano,Nanotool和纳米液工具的曝光得分与测量数据具有良好的相关性。基于定量和定性评估,纳米工具和斯托夫•管理员 - 纳米工具具有更高的全面优势。需要使用更多类型的纳米材料来评估不同工具的更多比较研究。

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    《RSC Advances》 |2019年第59期|共17页
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  • 正文语种 eng
  • 中图分类 化学;
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