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Impact of psychiatric disorders on patient satisfaction after Nissen Fundoplication

机译:精神疾病对尼森黄铜精神后患者满意度的影响

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Background Anxiety and depression have been associated with an increased perception of gastroesophageal reflux symptoms, but there is a paucity of data regarding the outcomes of laparoscopic Nissen Fundoplication (LNF) in this patient population. Methods We performed a retrospective cohort study including all patients undergoing LNF between 2011 and 2017. Patients were stratified by baseline usage of serotonin-modulating medication or benzodiazepines as a proxy for depression and anxiety, respectively. Outcome measures included postoperative gastroesophageal health-related quality of life (GERD-HRQL) scores and overall satisfaction rates after surgery. A p value of < 0.05 was considered statistically significant. Results The population consisted of 271 patients of which 103 patients had depression and 44 patients had anxiety. Patients with depression reported no significant difference in pre- or postoperative GERD-HRQL scores compared to patients without depression and long-term satisfaction rates after surgery were similar in both groups at 76% vs 71%, respectively (p = 0.55). Patients with anxiety reported higher baseline HRQL scores (34 vs. 29, p = 0.05). At long-term follow-up (15 months), patients with anxiety reported slightly worse HRQL scores compared to controls (7 vs. 4, p = 0.11) despite no difference in usage of anti-acid medications or need for endoscopic dilations between the two groups. Patients with anxiety were less likely to report being "satisfied" after surgery (40% vs. 71%, p = 0.01) compared to controls. Conclusion Patients with anxiety have higher subjective reporting of GERD symptoms and are more likely to report being "satisfied" during long-term follow-up after LNF. Patients on medication for depression appear to have similar reporting of GERD symptoms and derive as much benefit from LNF as patients that are not. While LNF does improve the symptom burden in patients with anxiety, satisfaction is rarely achieved in long-term follow-up.
机译:背景焦虑和抑郁症与胃食管反流症状的感知增加有关,但缺乏关于该患者人群腹腔镜尼森对腹腔镜的结果(LNF)的数据。方法采用回顾性队列研究,包括2011年和2017年间接受LNF的所有患者。患者通过基线使用血清素调节药物或苯并二嗪类动物分别为抑郁和焦虑的代理。结果措施包括术后胃食管健康相关的生活质量(GERD-HRQL)分数和手术后的总体满意度。 P值<0.05被认为是统计学上显着的。结果人口由271名患者组成,其中103名患者患有抑郁症,44名患者患有焦虑。抑郁症患者报告与没有抑郁症的患者的患者没有显着差异,并且在两组中分别在76%vs 71%的两组中相似的患者(P = 0.55),手术中的长期满意度。焦虑患者报告较高的基线HRQL评分(34 vs.29,P = 0.05)。在长期随访(15个月),焦虑患者报告与对照相比略微差,尽管使用抗酸药物的使用情况没有差异,但是在内窥镜扩张之间没有差异两组。与对照相比,焦虑患者不太可能报告“满意”(40%对71%,P = 0.01)。结论焦虑患者具有更高的GERD症状的主观报告,并且在LNF后长期随访期间更有可能报告“满意”。抑郁症药物的患者似乎具有类似的GERD症状的报告,并从LNF作为没有的患者那样多的益处。虽然LNF确实改善了焦虑患者的症状负担,但在长期随访中很少实现满意度。

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