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首页> 外文期刊>Pediatrics: Official Publication of the American Academy of Pediatrics >Influenza-associated pediatric deaths in the united states, 2004-2012
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Influenza-associated pediatric deaths in the united states, 2004-2012

机译：美国的流感相关的儿科死亡，2004-2012

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摘要

BACKGROUND: Influenza-associated deaths in children occur annually. We describe the epidemiology of influenza-associated pediatric deaths from the 2004-2005 through the 2011-2012 influenza seasons. METHODS: Deaths in children ,18 years of age with laboratoryconfirmed influenza virus infection were reported to the Centers for Disease Control and Prevention by using a standard case report form to collect data on demographic characteristics, medical conditions, clinical course, and laboratory results. Characteristics of children with no high-risk medical conditions were compared with those of children with high-risk medical conditions. RESULTS: From October 2004 through September 2012, 830 pediatric influenza-associated deaths were reported. The median age was 7 years (interquartile range: 1-12 years). Thirty-five percent of children died before hospital admission. Of 794 children with a known medical history, 43% had no high-risk medical conditions, 33% had neurologic disorders, and 12% had genetic or chromosomal disorders. Children without high-risk medical conditions were more likely to die before hospital admission (relative risk: 1.9; 95% confidence interval: 1.6-2.4) and within 3 days of symptom onset (relative risk: 1.6; 95% confidence interval: 1.3-2.0) than those with high-risk medical conditions. CONCLUSIONS: Influenza can be fatal in children with and without highrisk medical conditions. These findings highlight the importance of recommendations that all children should receive annual influenza vaccination to prevent influenza, and children who are hospitalized, who have severe illness, or who are at high risk of complications (age ,2 years or with medical conditions) should receive antiviral treatment as early as possible. Pediatrics 2013;132:796-804.
机译：背景：儿童的流感相关死亡每年发生。我们通过2011-2012流感季节描述了2004 - 2005年的流感相关儿科死亡的流行病学。方法：通过使用标准案例报告表将疾病控制和预防中心报告18岁的儿童死亡，18岁，通过使用标准案例报告表来收集关于人口统计特征，医疗条件，临床过程和实验室结果的数据。与具有高风险医疗条件的儿童进行比较没有高风险医疗病症的儿童的特征。结果：从2004年10月到2012年9月，报告了830个儿科的甲型流感相关死亡。中位年龄为7年（四分位数范围：1-12岁）。 35％的儿童在入院前死亡。在794名具有众所周知的病史儿童中，43％没有高风险的医疗条件，33％有神经系统疾病，12％有遗传或染色体疾病。在医院入院前（相对风险：1.9; 95％置信区间：1.6-2.4）和症状发作后3天内（相对风险：1.6; 95％：1.6; 95％置信区间：1.6; 95％置信区间：1.3 - 2.0）比具有高风险医疗状况的人。结论：流感在没有高常医疗条件的情况下，流感可能是致命的。这些发现强调了建议的重要性，所有孩子都应该接受每年流感疫苗接种以预防流感的植物，以及住院的儿童，他们存在严重疾病，或者处于高强度并发症（年龄，2年或医疗条件）应该接受尽早抗病毒治疗。 2013年儿科; 132：796-804。

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  • 作者

    WongK.K.; JainS.; BlantonL.; DharaR.; BrammerL.; FryA.M.; FinelliL.;

  • 作者单位

    Epidemic Intelligence Service Assigned to Influenza Division 1600 Clifton Rd NE MS E-03 Atlanta;

    Influenza Division Centers for Disease Control and Prevention Atlanta GA United States;

    Influenza Division Centers for Disease Control and Prevention Atlanta GA United States;

    Influenza Division Centers for Disease Control and Prevention Atlanta GA United States;

    Influenza Division Centers for Disease Control and Prevention Atlanta GA United States;

    Influenza Division Centers for Disease Control and Prevention Atlanta GA United States;

    Influenza Division Centers for Disease Control and Prevention Atlanta GA United States;

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  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类 儿科学;
  • 关键词

    Influenza; Mortality; Pediatric; Surveillance;

    机译：流感;死亡率;儿科;监督;

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