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首页> 外文期刊>Pediatrics: Official Publication of the American Academy of Pediatrics >Allergy testing in childhood: using allergen-specific IgE tests.
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Allergy testing in childhood: using allergen-specific IgE tests.

机译:儿童过敏测试:使用特定于过敏原的IgE测试。

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摘要

A variety of triggers can induce common pediatric allergic diseases which include asthma, allergic rhinitis, atopic dermatitis, food allergy, and anaphylaxis. Allergy testing serves to confirm an allergic trigger suspected on the basis of history. Tests for allergen-specific immunoglobulin E (IgE) are performed by in vitro assays or skin tests. The tests are excellent for identifying a sensitized state in which allergen-specific IgE is present, and may identify triggers to be eliminated and help guide immunotherapy treatment. However, a positive test result does not always equate with clinical allergy. Newer enzymatic assays based on anti-IgE antibodies have supplanted the radioallergosorbent test (RAST). This clinical report focuses on allergen-specific IgE testing, emphasizing that the medical history and knowledge of disease characteristics are crucial for rational test selection and interpretation.
机译:各种触发器可以诱导常见的儿科过敏性疾病,包括哮喘,过敏性鼻炎,特应性皮炎,食物过敏和过敏反应。 过敏测试用于确认在历史的基础上涉嫌怀疑的过敏触发。 通过体外测定或皮肤测试进行过敏原特异性免疫球蛋白E(IgE)的试验。 该试验非常适用于鉴定出现过敏原特异性IgE的敏化状态,并且可以识别待消除的触发器并帮助指导免疫治疗。 然而,阳性测试结果并不总是等同于临床过敏。 基于抗IgE抗体的新酶测定取代了放射性逆床试验(RAST)。 该临床报告侧重于特异性的IgE测试,强调疾病特征的病史和知识对于合理测试选择和解释至关重要。

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