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首页> 外文期刊>Current Science: A Fortnightly Journal of Research >Magnetic resonance functional neuroimaging: New insights into the human brain
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Magnetic resonance functional neuroimaging: New insights into the human brain

机译:磁共振功能神经成像:对人脑的新见解

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Magnetic resonance (MR) functional neuroimaging emerges as a new tool for mapping human brain functions at unsurpassed spatial resolution. The technique is noninvasive, widely available, and applicable to single subjects. Despite its tremendeous potential in cognitive neuroscience, ongoing methodologic developments pose significant challenges. They are mostly caused by the fact the MR detection of a focal change of brain activity is indirect and therefore relies on an unaffected neurovascular and/or neurometabolic coupling. This article describes some of the crucial elements necessary to transform a paradigm-related change in brain activity into a corresponding MR activation map. Pertinent examples range from data acquisition and signal processing to the underlying physiological mechanisms and details of the paradigm design.
机译:磁共振(MR)功能神经影像学已成为一种以无与伦比的空间分辨率绘制人脑功能的新工具。该技术是非侵入性的,可广泛使用,并且适用于单个受试者。尽管在认知神经科学领域具有巨大的潜力,但正在进行的方法学发展还是带来了巨大挑战。它们主要是由于对大脑活动的灶性变化的MR检测是间接的,因此依赖于未受影响的神经血管和/或神经代谢耦合。本文介绍了将与范式相关的大脑活动变化转换为相应的MR激活图所必需的一些关键要素。相关示例包括从数据采集和信号处理到底层的生理机制和范例设计的细节。

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