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首页> 外文期刊>Current opinion in anaesthesiology >Metabolic syndrome: anesthesia for morbid obesity.
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Metabolic syndrome: anesthesia for morbid obesity.

机译:代谢综合征:用于病态肥胖的麻醉。

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PURPOSE OF REVIEW: There is an emerging epidemic of obesity worldwide resulting in a greater number of obese patients presenting for surgery. The combined problems of metabolic disease and mechanical impairment from excess tissues present a variety of problems for the anesthesiologist. RECENT FINDINGS: Obesity is associated with nonalcoholic fatty liver disease, dyslipidemia, hyperglycemia and type 2 diabetes. Metabolic syndrome, a constellation of findings associated with visceral obesity, appears to confer additional long-term risk. To date no intervention has proven effective in reducing perioperative risk, although statin therapy is promising. Obese patients are more difficult to intubate in the 'sniffing' position, but placed in the 'ramped' position there is no evidence that this risk is greater than in the general population. Obstructive sleep apnea is associated with adverse postoperative outcomes. Much research has focused on preventing postoperative atelectasis. Preoxygenation with continuous positive airway pressure (CPAP), recruitment maneuvers, intraoperative positive end-expiratory pressure of at least 8 cmH2O and postextubation CPAP appear to improve postoperative pulmonary function. SUMMARY: Current studies have focused on the immediate impact of obesity on anesthesia and postoperative care. Future research will focus primarily on perioperative metabolic optimization.
机译:审查目的:全球范围内正在出现一种流行的肥胖病,导致越来越多的肥胖患者需要手术。代谢疾病和来自过量组织的机械损伤的综合问题为麻醉师带来了许多问题。最近发现:肥胖与非酒精性脂肪肝,血脂异常,高血糖和2型糖尿病有关。代谢综合征是与内脏肥胖相关的一系列发现,似乎赋予了更多的长期风险。迄今为止,尽管他汀类药物治疗前景广阔,但尚未有干预措施可有效降低围手术期风险。肥胖患者更难在“嗅探”位置插管,但置于“倾斜”位置没有证据表明这种风险大于普通人群。阻塞性睡眠呼吸暂停与不良的术后预后相关。许多研究集中在预防术后肺不张。持续气道正压通气(CPAP)的预充氧,招募动作,术中呼气末正压至少8 cmH2O和拔管后CPAP似乎可以改善术后肺功能。摘要:当前的研究集中在肥胖对麻醉和术后护理的直接影响。未来的研究将主要集中在围手术期代谢优化上。

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