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首页> 外文期刊>Current opinion in gastroenterology >Modern management of achalasia.
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Modern management of achalasia.

机译：门失弛缓症的现代管理。

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PURPOSE OF REVIEW: Achalasia is a chronic esophageal motility disorder characterized by incomplete lower esophageal sphincter relaxation and aperistalsis resulting in delayed esophageal emptying. Management is aimed at palliation of symptoms and improvement in quality of life. Multiple factors including demographics, severity of disease, and existing comorbidities influence management options. RECENT FINDINGS: Given its low rates of complications, surgical myotomy has become the preferred primary treatment, particularly in young males. However, recent studies describing favorable long-term outcomes for pneumatic dilation make this a reasonable option to consider as first-line therapy for achalasia. SUMMARY: Pneumatic dilation and surgical myotomy are the most effective therapeutic options for achalasia. Depending on local expertise, either option is acceptable as first-line therapy. There continues to be a limited role for other treatment modalities such as pharamacologic agents and botulinum toxin in certain patient populations.
机译：审查目的：失语症是一种慢性食管动力障碍，其特征是食管下括约肌松弛不完全和无精子症导致食管排空延迟。管理旨在减轻症状和改善生活质量。人口统计学，疾病严重程度和现有合并症等多种因素影响管理选择。最新发现：鉴于手术并发症的发生率低，它已成为首选的主要治疗方法，尤其是在年轻男性中。然而，最近的研究描述了气动扩张的长期良好效果，使之成为to门失弛缓症一线治疗的合理选择。摘要：气动扩张和手术肌切开术是门失弛缓症最有效的治疗选择。根据当地的专业知识，任何一种方法都可以作为一线治疗。在某些患者人群中，其他治疗方式（例如，药物，肉毒杆菌毒素）的作用仍然有限。

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