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Management of HCV and HIV infections among people who inject drugs.

机译:注射毒品者中HCV和HIV感染的管理。

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PURPOSE OF REVIEW: Despite a high burden of hepatitis C virus (HCV) and HIV infection among IDUs and the advent of effective therapies, assessment and treatment remain limited. The current review focuses on the management of HCV and HIV among IDUs, focusing particularly on recent strategies to enhance assessment, uptake and response to HCV and HIV treatment. RECENT FINDINGS: There are compelling data demonstrating that with the appropriate programs, treatment for HIV and HCV among IDUs is successful. However, assessment and treatment for HCV and HIV lags far behind the numbers of IDUs who could benefit from therapy, related to systems, provider and patient-related barriers to care. Strategies for enhancing assessment and treatment for HCV and HIV have been developed, including novel models integrating HCV/HIV care within existing community-based and drug and alcohol clinics, innovative methods for education delivery (including peer-support models) and directly observed therapy. SUMMARY: As we move forward, research must move beyond demonstrating that HCV and HIV infections can be successfully treated among IDUs. There is clear evidence that this is both feasible and effective. Novel strategies to enhance assessment, uptake and response to treatment should be evaluated among IDUs to elucidate mechanisms to enhance care for this underserved population.
机译:审查目的:尽管在注射毒品使用者中丙型肝炎病毒(HCV)和艾滋病毒感染负担很重,并且有效疗法的出现,评估和治疗仍然受到限制。当前的审查侧重于注射毒品使用者之间的丙型肝炎和艾滋病毒的管理,尤其侧重于近期加强对丙型肝炎和艾滋病毒治疗的评估,吸收和反应的战略。最近的发现:有令人信服的数据表明,通过适当的计划,IDU中HIV和HCV的治疗是成功的。但是,HCV和HIV的评估和治疗远远落后于可以从治疗中受益的IDU人数,这与系统,提供者和患者相关的护理障碍有关。已经制定了加强对HCV和HIV评估和治疗的策略,包括将HCV / HIV护理整合到现有社区和毒品与酒精诊所中的新颖模型,创新的教育方法(包括同伴支持模型)和直接观察的治疗。简介:随着我们的前进,研究必须超越证明IDU之间可以成功治疗HCV和HIV感染的领域。有明确的证据表明这既可行又有效。应该在注射吸毒者中评估提高评估,吸收和对治疗反应的新策略,以阐明增强对这一服务不足人群的护理的机制。

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