Breast cancer biomarkers: Risk assessment, diagnosis, prognosis, prediction of treatment efficacy and toxicity, and recurrence

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Breast cancer biomarkers: Risk assessment, diagnosis, prognosis, prediction of treatment efficacy and toxicity, and recurrence

机译：乳腺癌生物标志物：风险评估，诊断，预后，治疗效果和毒性预测以及复发

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Breast cancer is the most common cancer amongst women in the United States and around the world. Although widespread use of adjuvant chemotherapeutic and hormonal agents has improved mortality from breast cancer, it remains challenging to determine on an individual basis who will benefit from such treatments and who will be likely to encounter toxicities. With the rising costs of healthcare and the introduction of new targeted therapies, use of biomarkers has emerged as a method of assisting with breast cancer diagnosis, prognosis, prediction of therapeutic response, and surveillance of disease during and after treatment. In the following review, prognostic and therapeutic biomarkers, their utility in the management of patients with breast cancer, and current recommendations regarding their clinical use will be discussed.

机译：乳腺癌是美国和全世界女性中最常见的癌症。尽管辅助化疗和激素药物的广泛使用已提高了乳腺癌的死亡率，但仍然难以根据个人情况确定谁将从此类治疗中受益以及谁可能会遇到毒性。随着医疗保健费用的上涨和新靶向疗法的引入，生物标志物的使用已成为一种辅助乳腺癌诊断，预后，治疗反应预测以及治疗期间和治疗后疾病监测的方法。在下面的综述中，将讨论预后和治疗生物标志物，其在乳腺癌患者管理中的效用以及有关其临床用途的最新建议。

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《Current pharmaceutical design》 |2014年第30期|共20页
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正文语种 eng
中图分类药学;
关键词
Biomarker; Breast cancer; Carditoxicity; Diagnosis; Metastasis; Prognosis; Recurrence; Treatment;

机译：生物标志物;乳腺癌;心脏毒性;诊断;转移;预后;复发;治疗;

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1. Breast cancer biomarkers: Risk assessment, diagnosis, prognosis, prediction of treatment efficacy and toxicity, and recurrence [J] . Current pharmaceutical design . 2014,第30期

机译：乳腺癌生物标志物：风险评估，诊断，预后，治疗效果和毒性预测以及复发
2. Biomarkers for early diagnosis, prognosis, prediction, and recurrence monitoring of non-small cell lung cancer [J] . Yong Tang, Guibin Qiao, Enwu Xu, OncoTargets and therapy . 2017,第4期

机译：用于非小细胞肺癌的早期诊断，预后，预测和复发监测的生物标志物
3. Metabolomic Biomarkers of Prostate Cancer: Prediction, Diagnosis, Progression, Prognosis, and Recurrence [J] . Rachel S. Kelly, Matthew G. Ver Heiden, Edward Giovannucci, Cancer reviews . 2016,第Jula期

机译：前列腺癌的代谢组学生物标志物：预测，诊断，进展，预后和复发
4. Optical redox imaging of fixed unstained tissue slides to identify biomarkers for breast cancer diagnosis/prognosis: feasibility study [C] . He N. Xu, Julia Tchou, Yusheng Li, Conference on Diagnosis and Treatment of Diseases in the Breast and Reproductive System . 2018

机译：固定未染色的载玻片的光学氧化还原成像，以鉴定用于乳腺癌诊断/预后的生物标记物：可行性研究
5. Evaluation of quantitative MR imaging biomarkers for assessment of breast cancer risk. [D] . Xing, Ye. 2010

机译：定量MR成像生物标记物评估乳腺癌风险的评估。
6. Biomarkers for early diagnosis prognosis prediction and recurrence monitoring of non-small cell lung cancer [O] . Yong Tang, Guibin Qiao, Enwu Xu, 2017

机译：用于非小细胞肺癌的早期诊断预后预测和复发监测的生物标志物
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机译：P1246age-，身体大小和性别特异性参考Tricuspid阀装置参数通过实时三维经线性超声心动图124772777777747774747478EVALIGUTALMEXP1249预期植入前后MV环形植入前后MV环空性修饰。超声心动图参数用于成功的经截管边缘到边缘二尖瓣修复P1250中的体表面积诊断和结果患者假体在Tavi后的不匹配。是否有必要调整理想的体重？P1251矛盾的低流量低梯度严重，如Tavi：矛盾的VS平行于高梯度ASP1252的结果，在没有明显显着的心脏病和以前心血管事件的情况下心脏钙化的促傲作用患有心血管危险因素的添加剂值分数？没有传单脱垂的二尖瓣退化或作为严重二尖瓣血管血管血管病风险评估的患者进行脱垂或系绳，应当在偶然主动脉源肺源P1255Cariac阀钙化评分患者中进行：用于心血管风险分层的简单2D超声心动图工具在慢性肾功能衰竭的患者中，经沟管主动脉瓣膜置换术后：流行率，预测因子和对Otcomasp1257的影响，心肌缩短决定了导通延迟的心中的剩余心室区域重新耦合258MYCIARIAL僵硬评估使用剪切波成像在健康儿童和肥厚性心肌脑病中的舒缓性心脏响应，在渗透心肌肌瘤患者中使用载体速度成像的培养速度成像（高敏感的肌钙蛋白T和N-末端脑Natrietic肽）渗透心肌病，患者心室全局纵向菌株在患有心律失常右心室发育不良患者的心理心律失常患者中的青少年患者与Controlsp1262 echogrqphic预测因子的分歧，患者心血性右心室发育不良患者患者患者患者患者患者患者患者患者患者线粒体（ANT1）心肌病患者的喷射FRACTIONP1264系列响应1265心血管危险因素和癌症类型在蒽丙烯的心肌毒性皮1126660中的影响访问患有糖尿病母亲胎儿胎儿急性心肌炎的超声心动图，患者患者：胎儿计算模型分析P1268增加外膜脂肪组织与肾动脉狭窄患者肾脏灌注的应激诱导的心肌病，增强超声波：诊断和预后应用。

Breast cancer biomarkers: Risk assessment, diagnosis, prognosis, prediction of treatment efficacy and toxicity, and recurrence

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