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The Role of Archaeal Chromatin in Transcription

机译:archaeal染色质在转录中的作用

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Genomic organization impacts accessibility and movement of information processing systems along DNA. DNA-bound proteins dynamically dictate gene expression and provide regulatory potential to tune transcription rates to match ever-changing environmental conditions. Archaeal genomes are typically small, circular, gene dense, and organized either by histone proteins that are homologous to their eukaryotic counterparts, or small basic proteins that function analogously to bacterial nucleoid proteins. We review here how archaeal genomes are organized and how such organization impacts archaeal gene expression, focusing on conserved DNA-binding proteins within the Glade and the factors that are known to impact transcription initiation and elongation within protein-bound genomes. (C) 2019 Elsevier Ltd. All rights reserved.
机译:基因组组织沿DNA影响信息处理系统的可访问性和移动。 DNA结合的蛋白质动态地决定基因表达,并提供调节转录率的调节潜力,以匹配不断变化的环境条件。 古代基因组通常是小,圆形的,基因致密的,并且由与其真核同胞同源同源的组蛋白蛋白或类似于细菌核蛋白的小碱性蛋白质组织。 我们在这里审查了古代基因组织如何组织以及这种组织如何影响古群基因表达,重点是林林内的保守的DNA结合蛋白和蛋白质结合基因组中已知的因素。 (c)2019 Elsevier Ltd.保留所有权利。

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