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首页> 外文期刊>Abdominal imaging. >Multidetector CT in the evaluation of retroperitoneal fat tissue infiltration in ductal adenocarcinoma of the pancreatic head: correlation with histopathological findings.
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Multidetector CT in the evaluation of retroperitoneal fat tissue infiltration in ductal adenocarcinoma of the pancreatic head: correlation with histopathological findings.

机译：多层螺旋CT评价胰头导管腺癌腹膜后脂肪组织浸润：与组织病理学发现的关系。

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BACKGROUND: Neoplastic infiltration of the retroportal fat tissue is a critical parameter in tumor staging and in surgical planning because it frequently represents a site of persistence and recurrence of disease. METHOD: We evaluated 64 patients affected by ductal adenocarcinoma of the pancreatic head/uncinate process, submitted to curative surgery. Suspicion of infiltration (micro or macroinfiltration) of the retroportal margin arose at MDCT in cases of obliteration, irregularity, or abnormal density of the fatty layer localized between the medial surface of the pancreatic head/uncinate process and the mesenteric artery. RESULTS: CT suggested the infiltration of the retroportal tissue in 27 cases (10 microinfiltration, 17 macroinfiltration). At histopathology, the presence of infiltration was confirmed in 21/27 (78%) cases. In all CT cases of microinfiltration, the retroperitoneal resection margin was not infiltrated, while all cases (6) with infiltration of the retroperitoneal margin were macroinfiltrated at CT. The sensitivity of CT was 80%, specificity of 84% with an overall diagnostic accuracy of 82%. CONCLUSION: MDCT is accurate in the assessment of the neoplastic infiltration of the retroportal fat tissue.
机译：背景：直肠后脂肪组织的肿瘤浸润是肿瘤分期和手术计划中的关键参数，因为它经常代表疾病的持久性和复发性部位。方法：我们评估了64例受胰头/囊突性导管腺癌影响的患者，并接受了根治性手术。在闭塞，不规则或胰头/未弓突内侧表面与肠系膜动脉之间脂肪层密度异常，不规则的情况下，在MDCT上出现了后门边缘的浸润（微浸润或大浸润）。结果：CT提示27例后门组织浸润（10例微浸润，17例大浸润）。在组织病理学上，在21/27（78％）病例中证实存在浸润。在所有CT微浸润病例中，腹膜后切除切缘均未浸润，而所有腹膜后切缘浸润病例（6）均在CT处大浸润。 CT的敏感性为80％，特异性为84％，总诊断准确性为82％。结论：MDCT在评估后门脂肪组织的肿瘤浸润方面是准确的。

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